4-(4-((naphthalen-1-yloxy)methyl)-1H-1,2,3-triazol-1-yl)-N-phenethylbenzenesulfonamide

Base Information

Chemical Name:4-(4-((naphthalen-1-yloxy)methyl)-1H-1,2,3-triazol-1-yl)-N-phenethylbenzenesulfonamide
CAS No.:1456736-79-0
Molecular Formula:C₂₇H₂₄N₄O₃S
Molecular Weight:484.579
Hs Code.:

Synonyms:4-(4-((naphthalen-1-yloxy)methyl)-1H-1,2,3-triazol-1-yl)-N-phenethylbenzenesulfonamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4-(4-((naphthalen-1-yloxy)methyl)-1H-1,2,3-triazol-1-yl)-N-phenethylbenzenesulfonamide

Chemical Property:

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Technology Process of 4-(4-((naphthalen-1-yloxy)methyl)-1H-1,2,3-triazol-1-yl)-N-phenethylbenzenesulfonamide

There total 5 articles about 4-(4-((naphthalen-1-yloxy)methyl)-1H-1,2,3-triazol-1-yl)-N-phenethylbenzenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

: 18542-45-5
1-(propargyloxy)naphthalene

: 1456736-75-6
4-azido-N-phenethylbenzenesulfonamide

: 1456736-79-0
4-(4-((naphthalen-1-yloxy)methyl)-1H-1,2,3-triazol-1-yl)-N-phenethylbenzenesulfonamide

Guidance literature:: With Vitamin C; copper(II) sulfate pentahydrate; In water; tert-butyl alcohol; at 20 ℃; for 2h;
DOI:10.1007/s00044-013-0777-z

Reference yield:

: 587850-67-7
4-amino-N-phenethyl-benzenesulfonamide

: 1456736-79-0
4-(4-((naphthalen-1-yloxy)methyl)-1H-1,2,3-triazol-1-yl)-N-phenethylbenzenesulfonamide

Guidance literature:: Multi-step reaction with 2 steps

1.1: hydrogenchloride; acetic acid; sodium nitrite / water / 0.25 h / 0 °C

1.2: 0.5 h / 50 °C

2.1: copper(II) sulfate pentahydrate; Vitamin C / water; tert-butyl alcohol / 2 h / 20 °C

With hydrogenchloride; Vitamin C; copper(II) sulfate pentahydrate; acetic acid; sodium nitrite; In water; tert-butyl alcohol;
DOI:10.1007/s00044-013-0777-z

Reference yield:

: 52374-24-0
N-(4-nitrobenzenesulfonyl)-2-phenylethylamine

: 1456736-79-0
4-(4-((naphthalen-1-yloxy)methyl)-1H-1,2,3-triazol-1-yl)-N-phenethylbenzenesulfonamide

Guidance literature:: Multi-step reaction with 3 steps

1.1: tin(II) chloride dihdyrate / ethanol / 4 h / Reflux

2.1: hydrogenchloride; acetic acid; sodium nitrite / water / 0.25 h / 0 °C

2.2: 0.5 h / 50 °C

3.1: copper(II) sulfate pentahydrate; Vitamin C / water; tert-butyl alcohol / 2 h / 20 °C

With hydrogenchloride; tin(II) chloride dihdyrate; Vitamin C; copper(II) sulfate pentahydrate; acetic acid; sodium nitrite; In ethanol; water; tert-butyl alcohol;
DOI:10.1007/s00044-013-0777-z