(2S)-2-({(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy}methyl)-5-nitro-2-phenylpiperidine

Base Information

Chemical Name:(2S)-2-({(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy}methyl)-5-nitro-2-phenylpiperidine
CAS No.:1065272-03-8
Molecular Formula:C₂₂H₂₂F₆N₂O₃
Molecular Weight:476.419
Hs Code.:

Synonyms:(2S)-2-({(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy}methyl)-5-nitro-2-phenylpiperidine

Suppliers and Price of (2S)-2-({(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy}methyl)-5-nitro-2-phenylpiperidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of (2S)-2-({(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy}methyl)-5-nitro-2-phenylpiperidine

Chemical Property:

Purity/Quality:: 99% ^*data from raw suppliers

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Technology Process of (2S)-2-({(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy}methyl)-5-nitro-2-phenylpiperidine

There total 1 articles about (2S)-2-({(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy}methyl)-5-nitro-2-phenylpiperidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 873947-63-8
benzyl (2S)-2-({(1R)-1-[3,5-bis(tri-fluoro-methyl)-phenyl]ethoxy}-methyl)-5-nitro-2-phenylpiperidine-1-carboxylate

: 1065272-03-8
(2S)-2-({(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy}methyl)-5-nitro-2-phenylpiperidine

Guidance literature:: benzyl (2S)-2-({(1R)-1-[3,5-bis(tri-fluoro-methyl)-phenyl]ethoxy}-methyl)-5-nitro-2-phenylpiperidine-1-carboxylate; With hydrogenchloride; hydrogen; palladium 10% on activated carbon; In methanol; water; at 20 - 25 ℃; under 750.075 - 2250.23 Torr;

With sodium carbonate; In water; toluene; pH=9 - 10;

Reference yield: 50.0%

: 1065272-03-8
(2S)-2-({(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy}methyl)-5-nitro-2-phenylpiperidine

: 107-02-8,25068-14-8
acrolein

: 893425-65-5
C₂₅H₂₄F₆N₂O₃

Guidance literature:: (2S)-2-({(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy}methyl)-5-nitro-2-phenylpiperidine; acrolein; potassium carbonate; In methanol; at 20 ℃;

With ammonium chloride; In methanol; water;

With triethylamine; toluene-4-sulfonic acid; more than 3 stages;