C₄₄H₆₈O₈Si₂

Base Information

Chemical Name:C₄₄H₆₈O₈Si₂
CAS No.:880344-57-0
Molecular Formula:C₄₄H₆₈O₈Si₂
Molecular Weight:781.19
Hs Code.:

C<sub>44</sub>H<sub>68</sub>O<sub>8</sub>Si<sub>2</sub>

Synonyms:C₄₄H₆₈O₈Si₂

Suppliers and Price of C₄₄H₆₈O₈Si₂

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of C₄₄H₆₈O₈Si₂

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of C₄₄H₆₈O₈Si₂

There total 18 articles about C₄₄H₆₈O₈Si₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 157240-43-2
(4R)-4,5-isopropylidenedioxy-1-(dimethoxyphosphoryl)-2-pentanone

: 880344-57-0
C₄₄H₆₈O₈Si₂

Guidance literature:: Multi-step reaction with 21 steps

1.1: LiCl; N,N-diisopropylethylamine / acetonitrile / 2 h / 25 °C

1.2: 86 percent / acetonitrile / 15 h / 25 °C

2.1: 98 percent / LiI; LiAlH₄ / diethyl ether / -100 - 0 °C

3.1: 97 percent / AcOH / H₂O / 5 h / 40 °C

4.1: 70 percent / NaHCO₃; N-iodosuccinimide / tetrahydrofuran / 36 h / 0 °C

5.1: 99 percent / Et₃N; 4-(dimethylamino)pyridine / CH₂Cl₂ / 10 h / 25 °C

6.1: 100 percent / 2,6-lutidine / CH₂Cl₂ / 0.5 h / 0 °C

7.1: 99 percent / H₂; Raney-Ni catalyst / ethanol / 1 h / 25 °C

8.1: 88 percent / H₂ / Pd(OH)2/C / ethanol / 3 h / 25 °C

9.1: 99 percent / Dess-Martin periodinane / CH₂Cl₂ / 2 h / 0 - 25 °C

10.1: Mg / tetrahydrofuran / 2 h / 25 °C

10.2: tetrahydrofuran / 2 h / -78 - 0 °C

11.1: 95 percent / Dess-Martin periodinane / CH₂Cl₂ / 4 h / 0 - 25 °C

12.1: 98 percent / triethyl orthoformate; p-TsOH / 2.5 h / 55 °C

13.1: N-methylmorpholine-N-oxide; OsO₄ / tetrahydrofuran; H₂O; 2-methyl-propan-2-ol / 14 h / 25 °C

13.2: 100 percent / NaIO₄; aq. saline solution buffer / tetrahydrofuran; 2-methyl-propan-2-ol / 5 h / 25 °C

14.1: n-BuLi / tetrahydrofuran; toluene / 3 h / -30 °C

14.2: tetrahydrofuran / 1 h / -30 °C

15.1: 13.2 g / Dess-Martin periodinane; pyridine / CH₂Cl₂ / 2 h / 0 °C

16.1: 85 percent / TMSOTf / CH₂Cl₂ / 3 h / -78 - -30 °C

17.1: 95 percent / pyridine; 4-(dimethylamino)pyridine / CH₂Cl₂ / 3 h / 25 °C

18.1: 91 percent / 2,6-lutidine; N-bromosuccinimide / acetonitrile; H₂O / 2 h / 25 °C

19.1: 92 percent / NaBH₄ / methanol / 0.08 h / -5 °C

20.1: 56 percent / trifluoroacetic acid / CH₂Cl₂ / 3 h / 0 °C

21.1: 92 percent / imidazole; 4-DMAP / CH₂Cl₂ / 10 h / -78 - 0 °C

With pyridine; 1H-imidazole; 2,6-dimethylpyridine; dmap; sodium tetrahydroborate; N-Bromosuccinimide; N-iodo-succinimide; osmium(VIII) oxide; lithium aluminium tetrahydride; n-butyllithium; trimethylsilyl trifluoromethanesulfonate; Raney-Ni catalyst; hydrogen; sodium hydrogencarbonate; Dess-Martin periodane; toluene-4-sulfonic acid; magnesium; acetic acid; 4-methylmorpholine N-oxide; triethylamine; N-ethyl-N,N-diisopropylamine; orthoformic acid triethyl ester; trifluoroacetic acid; lithium chloride; lithium iodide; palladium dihydroxide; In tetrahydrofuran; methanol; diethyl ether; ethanol; dichloromethane; water; toluene; acetonitrile; tert-butyl alcohol;
DOI:10.1021/ja0547477

Reference yield:

: 392663-07-9
(2R,3S,5R)-2-((1S,2R)-3-Benzyloxy-1-iodo-2-methyl-propyl)-3-(tert-butyl-dimethyl-silanyloxy)-5-(tert-butyl-diphenyl-silanyloxymethyl)-tetrahydro-furan

: 880344-57-0
C₄₄H₆₈O₈Si₂

Guidance literature:: Multi-step reaction with 15 steps

1.1: 99 percent / H₂; Raney-Ni catalyst / ethanol / 1 h / 25 °C

2.1: 88 percent / H₂ / Pd(OH)2/C / ethanol / 3 h / 25 °C

3.1: 99 percent / Dess-Martin periodinane / CH₂Cl₂ / 2 h / 0 - 25 °C

4.1: Mg / tetrahydrofuran / 2 h / 25 °C

4.2: tetrahydrofuran / 2 h / -78 - 0 °C

5.1: 95 percent / Dess-Martin periodinane / CH₂Cl₂ / 4 h / 0 - 25 °C

6.1: 98 percent / triethyl orthoformate; p-TsOH / 2.5 h / 55 °C

7.1: N-methylmorpholine-N-oxide; OsO₄ / tetrahydrofuran; H₂O; 2-methyl-propan-2-ol / 14 h / 25 °C

7.2: 100 percent / NaIO₄; aq. saline solution buffer / tetrahydrofuran; 2-methyl-propan-2-ol / 5 h / 25 °C

8.1: n-BuLi / tetrahydrofuran; toluene / 3 h / -30 °C

8.2: tetrahydrofuran / 1 h / -30 °C

9.1: 13.2 g / Dess-Martin periodinane; pyridine / CH₂Cl₂ / 2 h / 0 °C

10.1: 85 percent / TMSOTf / CH₂Cl₂ / 3 h / -78 - -30 °C

11.1: 95 percent / pyridine; 4-(dimethylamino)pyridine / CH₂Cl₂ / 3 h / 25 °C

12.1: 91 percent / 2,6-lutidine; N-bromosuccinimide / acetonitrile; H₂O / 2 h / 25 °C

13.1: 92 percent / NaBH₄ / methanol / 0.08 h / -5 °C

14.1: 56 percent / trifluoroacetic acid / CH₂Cl₂ / 3 h / 0 °C

15.1: 92 percent / imidazole; 4-DMAP / CH₂Cl₂ / 10 h / -78 - 0 °C

With pyridine; 1H-imidazole; 2,6-dimethylpyridine; dmap; sodium tetrahydroborate; N-Bromosuccinimide; osmium(VIII) oxide; n-butyllithium; trimethylsilyl trifluoromethanesulfonate; Raney-Ni catalyst; hydrogen; Dess-Martin periodane; toluene-4-sulfonic acid; magnesium; 4-methylmorpholine N-oxide; orthoformic acid triethyl ester; trifluoroacetic acid; palladium dihydroxide; In tetrahydrofuran; methanol; ethanol; dichloromethane; water; toluene; acetonitrile; tert-butyl alcohol;
DOI:10.1021/ja0547477

Reference yield:

: 392663-03-5
(E)-(2R,4S,7S)-8-Benzyloxy-7-methyl-oct-5-ene-1,2,4-triol

: 880344-57-0
C₄₄H₆₈O₈Si₂

Guidance literature:: Multi-step reaction with 18 steps

1.1: 70 percent / NaHCO₃; N-iodosuccinimide / tetrahydrofuran / 36 h / 0 °C

2.1: 99 percent / Et₃N; 4-(dimethylamino)pyridine / CH₂Cl₂ / 10 h / 25 °C

3.1: 100 percent / 2,6-lutidine / CH₂Cl₂ / 0.5 h / 0 °C

4.1: 99 percent / H₂; Raney-Ni catalyst / ethanol / 1 h / 25 °C

5.1: 88 percent / H₂ / Pd(OH)2/C / ethanol / 3 h / 25 °C

6.1: 99 percent / Dess-Martin periodinane / CH₂Cl₂ / 2 h / 0 - 25 °C

7.1: Mg / tetrahydrofuran / 2 h / 25 °C

7.2: tetrahydrofuran / 2 h / -78 - 0 °C

8.1: 95 percent / Dess-Martin periodinane / CH₂Cl₂ / 4 h / 0 - 25 °C

9.1: 98 percent / triethyl orthoformate; p-TsOH / 2.5 h / 55 °C

10.1: N-methylmorpholine-N-oxide; OsO₄ / tetrahydrofuran; H₂O; 2-methyl-propan-2-ol / 14 h / 25 °C

10.2: 100 percent / NaIO₄; aq. saline solution buffer / tetrahydrofuran; 2-methyl-propan-2-ol / 5 h / 25 °C

11.1: n-BuLi / tetrahydrofuran; toluene / 3 h / -30 °C

11.2: tetrahydrofuran / 1 h / -30 °C

12.1: 13.2 g / Dess-Martin periodinane; pyridine / CH₂Cl₂ / 2 h / 0 °C

13.1: 85 percent / TMSOTf / CH₂Cl₂ / 3 h / -78 - -30 °C

14.1: 95 percent / pyridine; 4-(dimethylamino)pyridine / CH₂Cl₂ / 3 h / 25 °C

15.1: 91 percent / 2,6-lutidine; N-bromosuccinimide / acetonitrile; H₂O / 2 h / 25 °C

16.1: 92 percent / NaBH₄ / methanol / 0.08 h / -5 °C

17.1: 56 percent / trifluoroacetic acid / CH₂Cl₂ / 3 h / 0 °C

18.1: 92 percent / imidazole; 4-DMAP / CH₂Cl₂ / 10 h / -78 - 0 °C

With pyridine; 1H-imidazole; 2,6-dimethylpyridine; dmap; sodium tetrahydroborate; N-Bromosuccinimide; N-iodo-succinimide; osmium(VIII) oxide; n-butyllithium; trimethylsilyl trifluoromethanesulfonate; Raney-Ni catalyst; hydrogen; sodium hydrogencarbonate; Dess-Martin periodane; toluene-4-sulfonic acid; magnesium; 4-methylmorpholine N-oxide; triethylamine; orthoformic acid triethyl ester; trifluoroacetic acid; palladium dihydroxide; In tetrahydrofuran; methanol; ethanol; dichloromethane; water; toluene; acetonitrile; tert-butyl alcohol;
DOI:10.1021/ja0547477