Propanedinitrile, [[5-(methylphenylamino)-2-furanyl]methylene]- (9CI)

Base Information

• Chemical Name: Propanedinitrile, [[5-(methylphenylamino)-2-furanyl]methylene]- (9CI)
• CAS No.: 195298-65-8
• Molecular Formula: C₁₅H₁₁N₃O
• Molecular Weight: 249.272
• Mol file: 195298-65-8.mol

Synonyms:Propanedinitrile,[[5-(methylphenylamino)-2-furanyl]methylene]- (9CI)

Chemical Property of Propanedinitrile, [[5-(methylphenylamino)-2-furanyl]methylene]- (9CI)

Chemical Property:

• PSA: 0.00000
• LogP: 0.00000

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Propanedinitrile, [[5-(methylphenylamino)-2-furanyl]methylene]- (9CI)

There total 3 articles about Propanedinitrile, [[5-(methylphenylamino)-2-furanyl]methylene]- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

5-bromo-2-furancarboxaldehyde (1899-24-7) → 2-[5-(Methyl-phenyl-amino)-furan-2-ylmethylene]-malononitrile (195298-65-8)

Guidance literature:

Multi-step reaction with 3 steps

1: methanol / Heating

2: CH₃ONa / methanol; H₂O / 1 h / Ambient temperature

3: methanol; H₂O / 2 h / Ambient temperature

With sodium methylate; In methanol; water;

DOI:10.1135/cccc19971105

Reference yield:

Methyl-[5-[1-(methyl-phenyl-amino)-meth-(E)-ylidene]-5H-furan-(2E)-ylidene]-phenyl-ammonium; bromide → 2-[5-(Methyl-phenyl-amino)-furan-2-ylmethylene]-malononitrile (195298-65-8)

Guidance literature:

Multi-step reaction with 2 steps

1: CH₃ONa / methanol; H₂O / 1 h / Ambient temperature

2: methanol; H₂O / 2 h / Ambient temperature

With sodium methylate; In methanol; water;

DOI:10.1135/cccc19971105

Reference yield:

5-(N-methyl-anilino)-furan-2-carbaldehyde (22868-61-7) + malononitrile (109-77-3) → 2-[5-(Methyl-phenyl-amino)-furan-2-ylmethylene]-malononitrile (195298-65-8)

Guidance literature:

In methanol; water; for 2h; Yield given; Ambient temperature;

DOI:10.1135/cccc19971105

upstream raw materials:

5-(N-methyl-anilino)-furan-2-carbaldehyde

malononitrile

5-bromo-2-furancarboxaldehyde