1-(2-phenylethyl)-1H-indole-2,3-dione

Base Information

Chemical Name:1-(2-phenylethyl)-1H-indole-2,3-dione
CAS No.:41042-17-5
Molecular Formula:C₁₆H₁₃NO₂
Molecular Weight:251.285
Hs Code.:
DSSTox Substance ID:DTXSID201313648
Nikkaji Number:J3.085.151J
Pharos Ligand ID:R7M2A74ZBGFP
ChEMBL ID:CHEMBL3128205
Mol file:41042-17-5.mol

Synonyms:1-(2-phenylethyl)-1H-indole-2,3-dione;41042-17-5;1-phenethylindoline-2,3-dione;CHEMBL3128205;1-(2-phenylethyl)indole-2,3-dione;1-(2-phenylethyl)-2,3-dihydro-1H-indole-2,3-dione;1-Phenethyl-1H-indole-2,3-dione;1-(2-Phenylethyl)isatin;CBMicro_013192;SCHEMBL16799085;DTXSID201313648;SMSF0004372;BDBM50448804;STK038918;AKOS000245265;CB04560;CCG-105033;PD194990;BIM-0013407.P001;EN300-7443227;SR-01000411094;SR-01000411094-1;Z57493241;F0914-0816

Suppliers and Price of 1-(2-phenylethyl)-1H-indole-2,3-dione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of 1-(2-phenylethyl)-1H-indole-2,3-dione

Chemical Property:

XLogP3:2.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:251.094628657
Heavy Atom Count:19
Complexity:360

Purity/Quality:: 98%+ ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C=C1)CCN2C3=CC=CC=C3C(=O)C2=O

Technology Process of 1-(2-phenylethyl)-1H-indole-2,3-dione

There total 4 articles about 1-(2-phenylethyl)-1H-indole-2,3-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

: 839673-85-7
2-(bromophenyl)-N-(2-phenylethyl)acetamide

: 41042-17-5
1-(2-phenylethyl)-1H-indole-2,3-dione

Guidance literature:: With copper(l) iodide; 1,10-Phenanthroline; tetrabutylammomium bromide; potassium carbonate; In toluene; at 100 ℃; for 8h;
DOI:10.1039/c3ra40657a

Reference yield:

: 42366-35-8,1769-41-1
hydroxyimino-N-phenylacetamide

: 41042-17-5
1-(2-phenylethyl)-1H-indole-2,3-dione

Guidance literature:: Multi-step reaction with 2 steps

1.1: sulfuric acid / 1.25 h / 60 - 80 °C

2.1: sodium hydride / N,N-dimethyl-formamide / 0.5 h / 20 °C / Inert atmosphere

2.2: 20 °C / Inert atmosphere

With sulfuric acid; sodium hydride; In N,N-dimethyl-formamide; 1.1: |Sandmeyer Reaction;
DOI:10.1016/j.ejmech.2014.08.049

Reference yield:

: 62-53-3
aniline

: 41042-17-5
1-(2-phenylethyl)-1H-indole-2,3-dione

Guidance literature:: Multi-step reaction with 3 steps

1.1: sodium sulfate; hydroxylamine hydrochloride / 2 h / 80 - 90 °C / Acidic conditions

2.1: sulfuric acid / 1.25 h / 60 - 80 °C

3.1: sodium hydride / N,N-dimethyl-formamide / 0.5 h / 20 °C / Inert atmosphere

3.2: 20 °C / Inert atmosphere

With sulfuric acid; hydroxylamine hydrochloride; sodium hydride; sodium sulfate; In N,N-dimethyl-formamide; 2.1: |Sandmeyer Reaction;
DOI:10.1016/j.ejmech.2014.08.049