3-(2-(4-methoxybenzyl)-thiophenyl)-β-D-glucuronide

Base Information

• Chemical Name: 3-(2-(4-methoxybenzyl)-thiophenyl)-β-D-glucuronide
• CAS No.: 1215169-41-7
• Molecular Formula: C₁₈H₂₀O₈S
• Molecular Weight: 396.418
• Mol file: 1215169-41-7.mol

Synonyms:3-(2-(4-methoxybenzyl)-thiophenyl)-β-D-glucuronide

Chemical Property of 3-(2-(4-methoxybenzyl)-thiophenyl)-β-D-glucuronide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-(2-(4-methoxybenzyl)-thiophenyl)-β-D-glucuronide

There total 6 articles about 3-(2-(4-methoxybenzyl)-thiophenyl)-β-D-glucuronide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

3-O-(2-(4-methoxybenzyl)thiophenyl)-3,4,5-tri-O-acetyl-β-D-glucuronide (1215169-54-2) → 3-(2-(4-methoxybenzyl)-thiophenyl)-β-D-glucuronide (1215169-41-7)

Guidance literature:

3-O-(2-(4-methoxybenzyl)thiophenyl)-3,4,5-tri-O-acetyl-β-D-glucuronide; With methanol; sodium methylate; at 20 ℃; Inert atmosphere;

With hydrogenchloride; In methanol; ethanol; at 20 ℃; pH=6.5; Inert atmosphere;

DOI:10.1016/j.tet.2009.12.003

Reference yield: 74.0%

3-(2-(4-methoxybenzyl)-thiophenyl)-β-D-glucuronic methyl ester (1215169-56-4) → 3-(2-(4-methoxybenzyl)-thiophenyl)-β-D-glucuronide (1215169-41-7)

Guidance literature:

3-(2-(4-methoxybenzyl)-thiophenyl)-β-D-glucuronic methyl ester; With methanol; sodium methylate; at 20 ℃; Inert atmosphere;

With water; lithium chloride; In methanol; at 20 ℃; Inert atmosphere;

With hydrogenchloride; In methanol; water; pH=5.5;

DOI:10.1016/j.tet.2009.12.003

Reference yield:

C34H40O7SSi (1215169-69-9) → 3-(2-(4-methoxybenzyl)-thiophenyl)-β-D-glucuronide (1215169-41-7)

Guidance literature:

Multi-step reaction with 4 steps

1: pyridine

2: pyridine hydrogenfluoride

3: pyridine; Dess-Martin periodane

4: sodium methylate

With pyridine; sodium methylate; Dess-Martin periodane; pyridine hydrogenfluoride;

DOI:10.3998/ark.5550190.0013.319

upstream raw materials:

3-O-(2-(4-methoxybenzyl)thiophenyl)-3,4,5-tri-O-acetyl-β-D-glucuronide

3-(2-(4-methoxybenzyl)-thiophenyl)-β-D-glucuronic methyl ester

C₃₄H₄₀O₇SSi

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