Nα-2,3-dihydroxybenzoyl-L-ornithinyl-L-serine tert-butyl ester

Base Information

• Chemical Name: Nα-2,3-dihydroxybenzoyl-L-ornithinyl-L-serine tert-butyl ester
• CAS No.: 1027343-16-3
• Molecular Formula: C₁₉H₂₉N₃O₇
• Molecular Weight: 411.455
• Mol file: 1027343-16-3.mol

Synonyms:Nα-2,3-dihydroxybenzoyl-L-ornithinyl-L-serine tert-butyl ester

Chemical Property of Nα-2,3-dihydroxybenzoyl-L-ornithinyl-L-serine tert-butyl ester

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of Nα-2,3-dihydroxybenzoyl-L-ornithinyl-L-serine tert-butyl ester

There total 1 articles about Nα-2,3-dihydroxybenzoyl-L-ornithinyl-L-serine tert-butyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Nα-2,3-dibenzyloxybenzoyl-Nδ-benzyloxycarbonyl-L-ornithinyl-L-serine tert-butyl ester (937393-46-9) → Nα-2,3-dihydroxybenzoyl-L-ornithinyl-L-serine tert-butyl ester (1027343-16-3)

Guidance literature:

With 5% Pd/C; hydrogen; In methanol; at 20 ℃; for 3h;

DOI:10.1039/b719713f

Reference yield: 100.0%

Nα-2,3-dihydroxybenzoyl-L-ornithinyl-L-serine tert-butyl ester (1027343-16-3) → Nα-2,3-dihydroxybenzoyl-L-ornithinyl-L-serine (243971-34-8)

Guidance literature:

With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 16h;

DOI:10.1039/b719713f

Reference yield: 73.0%

Nα-2,3-dihydroxybenzoyl-L-ornithinyl-L-serine tert-butyl ester (1027343-16-3) + 1,3-di(tert-butyloxycarbonyl)-2-(trifluoromethylsulfonyl)guanidine (207857-15-6) → Nα-2,3-dihydroxybenzoyl-Nω-tert-butoxycarbonyl-Nω'-tert-butoxycarbonyl-L-argininyl-L-serine tert-butyl ester

Guidance literature:

With triethylamine; In chloroform; at 20 ℃; for 1h;

DOI:10.1039/b719713f

upstream raw materials:

Nα-2,3-dibenzyloxybenzoyl-Nδ-benzyloxycarbonyl-L-ornithinyl-L-serine tert-butyl ester

Downstream raw materials:

Nα-2,3-dihydroxybenzoyl-L-ornithinyl-L-serine