2-Ethoxy-5-[(4-methylpiperazin-1-yl)sulfonyl]benzoic acid

Base Information

Chemical Name:2-Ethoxy-5-[(4-methylpiperazin-1-yl)sulfonyl]benzoic acid
CAS No.:194602-23-8
Molecular Formula:C14H20 N2 O5 S
Molecular Weight:328.389
Hs Code.:
European Community (EC) Number:424-110-7,641-941-2
DSSTox Substance ID:DTXSID10478256
Metabolomics Workbench ID:60342
Nikkaji Number:J1.385.345B
Wikidata:Q27126395
Mol file:194602-23-8.mol

Synonyms:194602-23-8;2-ethoxy-5-[(4-methylpiperazin-1-yl)sulfonyl]benzoic acid;2-ethoxy-5-(4-methylpiperazin-1-yl)sulfonylbenzoic acid;2-ethoxy-5-(4-methyl-1-piperazinylsulfonyl)benzoic acid;2-Ethoxy-5-[(4-methyl-1-piperazinyl)sulfonyl]benzoic Acid;TXKSEEXWAGLOIY-UHFFFAOYSA-N;Benzoic acid, 2-ethoxy-5-[(4-methyl-1-piperazinyl)sulfonyl]-;SCHEMBL4551788;CHEBI:59007;DTXSID10478256;2-Ethoxy-5-[(4-methyl-1-piperazinyl)-sulfonyl]-benzoic acid;AKOS028112089;FT-0744329;NS00005911;EN300-214844;Q27126395;2-ethoxy-5(4methylpiperazin-1-ylsulphonyl)benzoic acid;2-ethoxy-5-(4-methyl-1-piperazinyisulfonyl)benzoic acid;2-Ethoxy-5-(4-methylpiperazine-1-sulfonyl)benzoic acid;Z381468586;2-ethoxy-5-(4-methylpiperazin-1-ylsulphonyl)benzoic acid;2-ethoxy-5-[(4-methylpiperazin-1-yl)sulfonyl]benzoicacid

Suppliers and Price of 2-Ethoxy-5-[(4-methylpiperazin-1-yl)sulfonyl]benzoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-Ethoxy-5-(4-methyl-1-piperazinylsulfonyl)benzoicAcid
100mg
$ 525.00

American Custom Chemicals Corporation
2-ETHOXY-5-(4-METHYL-1-PIPERAZINYLSULFONYL)BENZOIC ACID 95.00%
1G
$ 669.90

American Custom Chemicals Corporation
2-ETHOXY-5-(4-METHYL-1-PIPERAZINYLSULFONYL)BENZOIC ACID 95.00%
500MG
$ 646.80

American Custom Chemicals Corporation
2-ETHOXY-5-(4-METHYL-1-PIPERAZINYLSULFONYL)BENZOIC ACID 95.00%
10G
$ 1871.10

American Custom Chemicals Corporation
2-ETHOXY-5-(4-METHYL-1-PIPERAZINYLSULFONYL)BENZOIC ACID 95.00%
5G
$ 1120.35

AK Scientific
2-Ethoxy-5-(4-methylpiperazin-1-yl)sulfonylbenzoicacid
500mg
$ 822.00

Total 16 raw suppliers

Chemical Property of 2-Ethoxy-5-[(4-methylpiperazin-1-yl)sulfonyl]benzoic acid

Chemical Property:

Vapor Pressure:0Pa at 10.6℃
Boiling Point:507.0±60.0 °C(Predicted)
PKA:3.79±0.10(Predicted)
PSA：95.53000
Density:1.319±0.06 g/cm3(Predicted)
LogP:1.67620
XLogP3:-1.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:5
Exact Mass:328.10929292
Heavy Atom Count:22
Complexity:482

Purity/Quality:

99%, ^*data from raw suppliers

2-Ethoxy-5-(4-methyl-1-piperazinylsulfonyl)benzoicAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCOC1=C(C=C(C=C1)S(=O)(=O)N2CCN(CC2)C)C(=O)O
Uses 2-Ethoxy-5-(4-methyl-1-piperazinylsulfonyl)benzoic Acid is used as a reactant in the synthesis of Sildenafil Citrate (S435000), an orally active selective type 5 cGMP phosphodiesterase inhibitor.

Technology Process of 2-Ethoxy-5-[(4-methylpiperazin-1-yl)sulfonyl]benzoic acid

There total 10 articles about 2-Ethoxy-5-[(4-methylpiperazin-1-yl)sulfonyl]benzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%