Dimethyl-[(Z)-3-methylsulfanyl-3-(4-nitro-phenyl)-allyl]-amine

Base Information

• Chemical Name: Dimethyl-[(Z)-3-methylsulfanyl-3-(4-nitro-phenyl)-allyl]-amine
• CAS No.: 78089-97-1
• Molecular Formula: C₁₂H₁₆N₂O₂S
• Molecular Weight: 252.337
• Mol file: 78089-97-1.mol

Synonyms:Dimethyl-[(Z)-3-methylsulfanyl-3-(4-nitro-phenyl)-allyl]-amine

Chemical Property of Dimethyl-[(Z)-3-methylsulfanyl-3-(4-nitro-phenyl)-allyl]-amine

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of Dimethyl-[(Z)-3-methylsulfanyl-3-(4-nitro-phenyl)-allyl]-amine

There total 6 articles about Dimethyl-[(Z)-3-methylsulfanyl-3-(4-nitro-phenyl)-allyl]-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 53.0%

Dimethyl-[(E)-3-methylsulfanyl-3-(4-nitro-phenyl)-allylidene]-ammonium; iodide (78089-94-8) → Dimethyl-[(E)-3-methylsulfanyl-3-(4-nitro-phenyl)-allyl]-amine (78089-97-1) + Dimethyl-[(Z)-3-methylsulfanyl-3-(4-nitro-phenyl)-allyl]-amine (78089-97-1)

Guidance literature:

With sodium tetrahydroborate; In methanol; for 0.5h; Title compound not separated from byproducts;

DOI:10.1021/jo00331a032

Reference yield: 53.0%

Dimethyl-[(E)-3-methylsulfanyl-3-(4-nitro-phenyl)-allylidene]-ammonium; iodide (78089-94-8) → Dimethyl-[(E)-3-methylsulfanyl-3-(4-nitro-phenyl)-allyl]-amine (78089-97-1) + Dimethyl-[(Z)-3-methylsulfanyl-3-(4-nitro-phenyl)-allyl]-amine (78089-97-1)

Guidance literature:

With sodium tetrahydroborate; In methanol; for 0.5h; Title compound not separated from byproducts;

DOI:10.1021/jo00331a032

Reference yield:

(E)-3-dimethylamino-1-(4-nitrophenyl)-2-propen-1-one (78089-99-3) → Dimethyl-[(E)-3-methylsulfanyl-3-(4-nitro-phenyl)-allyl]-amine (78089-97-1)

Guidance literature:

Multi-step reaction with 3 steps

1: 32 percent / P₂S₅ / benzene / Heating

2: tetrahydrofuran / 2 h / Ambient temperature

3: 53 percent / NaBH₄ / methanol / 0.5 h

With sodium tetrahydroborate; tetraphosphorus decasulfide; In tetrahydrofuran; methanol; benzene;

DOI:10.1021/jo00331a032

upstream raw materials:

Dimethyl-[(E)-3-methylsulfanyl-3-(4-nitro-phenyl)-allylidene]-ammonium; iodide

(E)-3-dimethylamino-1-(4-nitrophenyl)-2-propen-1-one

3-N,N-Dimethylamino-1-(4-nitrophenyl)-prop-2-en-1-thion