2-<2-(1,3-dioxolan-2-yl)ethyl>-1-(4-fluorophenyl)-4-methyl-1,3-pentanedione

Base Information

Chemical Name:2-<2-(1,3-dioxolan-2-yl)ethyl>-1-(4-fluorophenyl)-4-methyl-1,3-pentanedione
CAS No.:116645-13-7
Molecular Formula:C₁₇H₂₁FO₄
Molecular Weight:308.35
Hs Code.:

Synonyms:2-<2-(1,3-dioxolan-2-yl)ethyl>-1-(4-fluorophenyl)-4-methyl-1,3-pentanedione

Suppliers and Price of 2-<2-(1,3-dioxolan-2-yl)ethyl>-1-(4-fluorophenyl)-4-methyl-1,3-pentanedione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2-<2-(1,3-dioxolan-2-yl)ethyl>-1-(4-fluorophenyl)-4-methyl-1,3-pentanedione

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-<2-(1,3-dioxolan-2-yl)ethyl>-1-(4-fluorophenyl)-4-methyl-1,3-pentanedione

There total 3 articles about 2-<2-(1,3-dioxolan-2-yl)ethyl>-1-(4-fluorophenyl)-4-methyl-1,3-pentanedione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 18742-02-4
2-bromo-2-(2-ethyl)dioxolane

hexane-washed sodium hydride: hexane-washed sodium hydride

: 114433-94-2
1-(4-Fluorophenyl)-3-isopropylpropan-1,3-dione

: 116645-13-7
2-<2-(1,3-dioxolan-2-yl)ethyl>-1-(4-fluorophenyl)-4-methyl-1,3-pentanedione

Guidance literature:: With sodium iodide; In N-methyl-acetamide; ice-water;

Reference yield:

: 403-42-9
1-(4-fluorophenyl)ethanone

: 116645-13-7
2-<2-(1,3-dioxolan-2-yl)ethyl>-1-(4-fluorophenyl)-4-methyl-1,3-pentanedione

Guidance literature:: Multi-step reaction with 2 steps

1: 50 percent / NaH / dioxane / 4 h / 80 - 90 °C

2: 1.) NaH, 2.) NaI / 1.) DMF, 2.) 80 to 90 deg C, 36 h

With sodium hydride; sodium iodide; In 1,4-dioxane;
DOI:10.1021/jm00163a006

Reference yield:

: 18742-02-4
2-bromo-2-(2-ethyl)dioxolane

: 114433-94-2
1-(4-Fluorophenyl)-3-isopropylpropan-1,3-dione

: 116645-13-7
2-<2-(1,3-dioxolan-2-yl)ethyl>-1-(4-fluorophenyl)-4-methyl-1,3-pentanedione

Guidance literature:: With sodium hydride; sodium iodide; Yield given. Multistep reaction; 1.) DMF, 2.) 80 to 90 deg C, 36 h;
DOI:10.1021/jm00163a006