ZC₃M-AE-NHS

Base Information

• Chemical Name: ZC₃M-AE-NHS
• CAS No.: 1307864-00-1
• Molecular Formula: C₃₈H₄₃N₃O₁₃S₂
• Molecular Weight: 813.904
• Mol file: 1307864-00-1.mol

Synonyms:ZC₃M-AE-NHS

Chemical Property of ZC₃M-AE-NHS

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of ZC₃M-AE-NHS

There total 13 articles about ZC₃M-AE-NHS which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

C34H40N2O11S2 (1307863-99-5) + O-(N-succinimidyl)-N,N,N',N'-tetramethyluronium tetrafluoroborate (105832-38-0) → ZC3M-AE-NHS (1307864-00-1)

Guidance literature:

With N-ethyl-N,N-diisopropylamine; In water; N,N-dimethyl-formamide; at 20 ℃; for 0.25h;

Reference yield:

C24H19NO5 (1307863-96-2) → ZC3M-AE-NHS (1307864-00-1)

Guidance literature:

Multi-step reaction with 4 steps

1: triphenylphosphine; di-isopropyl azodicarboxylate / tetrahydrofuran / 1 h / 20 °C / Inert atmosphere

2: 3-butyl-1-methyl-1H-imidazol-3-ium hexafluorophosphate; 2,6-di-tert-butyl-pyridine / 24 h / 150 °C

3: hydrogenchloride / water / 2 h / Inert atmosphere; Reflux

4: N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide; water / 0.25 h / 20 °C

With hydrogenchloride; 2,6-di-tert-butyl-pyridine; di-isopropyl azodicarboxylate; N-ethyl-N,N-diisopropylamine; triphenylphosphine; 3-butyl-1-methyl-1H-imidazol-3-ium hexafluorophosphate; In tetrahydrofuran; water; N,N-dimethyl-formamide;

Reference yield:

C29H30N2O5 (1307863-97-3) → ZC3M-AE-NHS (1307864-00-1)

Guidance literature:

Multi-step reaction with 3 steps

1: 3-butyl-1-methyl-1H-imidazol-3-ium hexafluorophosphate; 2,6-di-tert-butyl-pyridine / 24 h / 150 °C

2: hydrogenchloride / water / 2 h / Inert atmosphere; Reflux

3: N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide; water / 0.25 h / 20 °C

With hydrogenchloride; 2,6-di-tert-butyl-pyridine; N-ethyl-N,N-diisopropylamine; 3-butyl-1-methyl-1H-imidazol-3-ium hexafluorophosphate; In water; N,N-dimethyl-formamide;

upstream raw materials:

C₃₄H₄₀N₂O₁₁S₂

O-(N-succinimidyl)-N,N,N',N'-tetramethyluronium tetrafluoroborate

3-Dimethylamino-1-propanol

C₂₄H₁₉NO₅

Downstream raw materials:

C₅₃H₇₂N₆O₁₈S₃

C₄₄H₆₃N₅O₁₃S₃