4-(3-((S)-1-tert-butoxy-1-oxo-3-phenylpropan-2-ylamino)-3-oxopropyl)-2-cyclohexyl-5-oxo-2,5-dihydrooxazole 3-oxide

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Chemical Name:4-(3-((S)-1-tert-butoxy-1-oxo-3-phenylpropan-2-ylamino)-3-oxopropyl)-2-cyclohexyl-5-oxo-2,5-dihydrooxazole 3-oxide
CAS No.:1221411-38-6
Molecular Formula:C₂₅H₃₄N₂O₆
Molecular Weight:458.555
Hs Code.:

Synonyms:4-(3-((S)-1-tert-butoxy-1-oxo-3-phenylpropan-2-ylamino)-3-oxopropyl)-2-cyclohexyl-5-oxo-2,5-dihydrooxazole 3-oxide

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Chemical Property of 4-(3-((S)-1-tert-butoxy-1-oxo-3-phenylpropan-2-ylamino)-3-oxopropyl)-2-cyclohexyl-5-oxo-2,5-dihydrooxazole 3-oxide

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Technology Process of 4-(3-((S)-1-tert-butoxy-1-oxo-3-phenylpropan-2-ylamino)-3-oxopropyl)-2-cyclohexyl-5-oxo-2,5-dihydrooxazole 3-oxide

There total 1 articles about 4-(3-((S)-1-tert-butoxy-1-oxo-3-phenylpropan-2-ylamino)-3-oxopropyl)-2-cyclohexyl-5-oxo-2,5-dihydrooxazole 3-oxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 1221411-37-5
4-(2-carboxyethyl)-2-cyclohexyl-5-oxo-2,5-dihydrooxazole 3-oxide

: 15100-75-1,75898-47-4
L-phenylalanine tert-butyl ester hydrochloride

: 1221411-38-6
4-(3-((S)-1-tert-butoxy-1-oxo-3-phenylpropan-2-ylamino)-3-oxopropyl)-2-cyclohexyl-5-oxo-2,5-dihydrooxazole 3-oxide

Guidance literature:: With O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; at 20 ℃; for 18h;
DOI:10.1021/ol100467t

Reference yield: 81.0%

: 1221411-38-6
4-(3-((S)-1-tert-butoxy-1-oxo-3-phenylpropan-2-ylamino)-3-oxopropyl)-2-cyclohexyl-5-oxo-2,5-dihydrooxazole 3-oxide

: 1221411-49-9
(S)-tert-butyl 2-(3-(2-cyclohexyl-5-oxo-2,5-dihydrooxazol-4-yl)propanamido)-3-phenylpropanoate

Guidance literature:: With ammonium chloride; zinc; In tetrahydrofuran; water; at 20 ℃; for 0.5h;
DOI:10.1021/ol100467t

Reference yield: 71.0%

: 1221411-38-6
4-(3-((S)-1-tert-butoxy-1-oxo-3-phenylpropan-2-ylamino)-3-oxopropyl)-2-cyclohexyl-5-oxo-2,5-dihydrooxazole 3-oxide

: 1221411-39-7
1-((S)-1-(tert-butoxy)-1-oxo-3-phenylpropan-2-yl)-2-hydroxy-5-oxopyrrolidine-2-carboxylid acid

Guidance literature:: 4-(3-((S)-1-tert-butoxy-1-oxo-3-phenylpropan-2-ylamino)-3-oxopropyl)-2-cyclohexyl-5-oxo-2,5-dihydrooxazole 3-oxide; With ammonium chloride; zinc; In tetrahydrofuran; water; at 20 ℃; for 0.5h;

With oxalic acid; In tetrahydrofuran; water; at 35 ℃; for 4h;
DOI:10.1021/ol100467t