2-(4-isobutylphenyl)-2-methyl-4-pentynoic acid

Base Information

• Chemical Name: 2-(4-isobutylphenyl)-2-methyl-4-pentynoic acid
• CAS No.: 1374600-88-0
• Molecular Formula: C₁₆H₂₀O₂
• Molecular Weight: 244.334

Synonyms:2-(4-isobutylphenyl)-2-methyl-4-pentynoic acid

Chemical Property of 2-(4-isobutylphenyl)-2-methyl-4-pentynoic acid

Chemical Property:

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Technology Process of 2-(4-isobutylphenyl)-2-methyl-4-pentynoic acid

There total 1 articles about 2-(4-isobutylphenyl)-2-methyl-4-pentynoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

C17H22O2 → 2-(4-isobutylphenyl)-2-methyl-4-pentynoic acid (1374600-88-0)

Guidance literature:

C₁₇H₂₂O₂; With water; potassium hydroxide; In methanol; at 0 ℃; Inert atmosphere; Reflux;

With hydrogenchloride; In methanol; water;

DOI:10.1021/jo1013228

Reference yield: 92.0%

2-(4-isobutylphenyl)-2-methyl-4-pentynoic acid (1374600-88-0) + 1,2-diamino-benzene (95-54-5) → rac-(2R,3aR)-2-(4-isobutylphenyl)-2,3a-dimethyl-2,3,3a,4-tetrahydro-1H-benzo[d]pyrrolo[1,2-a]imidazol-1-one

Guidance literature:

With (triphenylphosphine)gold(I) chloride; silver trifluoromethanesulfonate; In 1,2-dichloro-ethane; at 100 ℃; for 24h; diastereoselective reaction; Inert atmosphere;

DOI:10.1021/jo1013228

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