C₃₀H₂₆O₅

Base Information

• Chemical Name: C₃₀H₂₆O₅
• CAS No.: 951776-65-1
• Molecular Formula: C₃₀H₂₆O₅
• Molecular Weight: 466.533
• Mol file: 951776-65-1.mol

Synonyms:C₃₀H₂₆O₅

Chemical Property of C₃₀H₂₆O₅

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₃₀H₂₆O₅

There total 10 articles about C₃₀H₂₆O₅ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

C37H32O5 (951776-84-4) → C30H26O5 (951776-65-1)

Guidance literature:

With methylaluminum dichloride; In hexane; dichloromethane; at -78 ℃; for 0.25h;

DOI:10.1021/ol7014219

Reference yield:

(2Z,4E)-3-Chloro-4-methyl-hexa-2,4-dienoic acid ethyl ester (864158-12-3) → C30H26O5 (951776-65-1)

Guidance literature:

Multi-step reaction with 6 steps

1.1: NaH; DMSO / 1 h / 20 °C

1.2: 36 percent / 15-crown-5 / dimethylsulfoxide / 60 h / 45 °C

2.1: MeAlCl₂; HSiEt₃ / CH₂Cl₂; hexane / 0 - 20 °C

2.2: 51 percent / K₂CO₃ / acetone / 15 h / Heating

3.1: NaOH / 1,2-dimethoxy-ethane / Heating

4.1: 300 mg / CH₂Cl₂ / 20 h / 20 °C

5.1: 79 percent / sodium dithionite; KOH / tetrahydrofuran; H₂O / 3 h / 0 °C

6.1: 99 percent / MeAlCl₂ / CH₂Cl₂; hexane / 0.25 h / -78 °C

With triethylsilane; potassium hydroxide; sodium hydroxide; sodium dithionite; methylaluminum dichloride; sodium hydride; dimethyl sulfoxide; In tetrahydrofuran; 1,2-dimethoxyethane; hexane; dichloromethane; water;

DOI:10.1021/ol7014219

Reference yield:

methyl 2-{[tert-butyl(dimethyl)silyl]oxy}-4-methylbenzoate (144033-44-3) → C30H26O5 (951776-65-1)

Guidance literature:

Multi-step reaction with 8 steps

1.1: toluene / 1 h / 20 °C

1.2: 85 percent / toluene / 16 h / 90 °C

2.1: t-BuLi; TMEDA / tetrahydrofuran; pentane / -78 - 0 °C

2.2: TBAF / tetrahydrofuran; pentane / 0.5 h / 20 °C

2.3: 88 percent / aq. HCl; acetic acid / tetrahydrofuran; pentane / 20 °C

3.1: NaH; DMSO / 1 h / 20 °C

3.2: 36 percent / 15-crown-5 / dimethylsulfoxide / 60 h / 45 °C

4.1: MeAlCl₂; HSiEt₃ / CH₂Cl₂; hexane / 0 - 20 °C

4.2: 51 percent / K₂CO₃ / acetone / 15 h / Heating

5.1: NaOH / 1,2-dimethoxy-ethane / Heating

6.1: 300 mg / CH₂Cl₂ / 20 h / 20 °C

7.1: 79 percent / sodium dithionite; KOH / tetrahydrofuran; H₂O / 3 h / 0 °C

8.1: 99 percent / MeAlCl₂ / CH₂Cl₂; hexane / 0.25 h / -78 °C

With triethylsilane; potassium hydroxide; sodium hydroxide; sodium dithionite; N,N,N,N,-tetramethylethylenediamine; tert.-butyl lithium; methylaluminum dichloride; sodium hydride; dimethyl sulfoxide; In tetrahydrofuran; 1,2-dimethoxyethane; hexane; dichloromethane; water; toluene; pentane;

DOI:10.1021/ol7014219

upstream raw materials:

C₃₇H₃₂O₅

(2Z,4E)-3-Chloro-4-methyl-hexa-2,4-dienoic acid ethyl ester

methyl 2-{[tert-butyl(dimethyl)silyl]oxy}-4-methylbenzoate

N,N-diethyl-2-(tert-butyldimethylsilyloxy)-4-methylbenzamide

Downstream raw materials:

C₃₂H₂₉BrO₅