4-Azido-3-chlorobenzyl bromide

Base Information

Chemical Name:4-Azido-3-chlorobenzyl bromide
CAS No.:193887-70-6
Molecular Formula:C7H5 Br Cl N3
Molecular Weight:246.494
Hs Code.:
DSSTox Substance ID:DTXSID50467306
Nikkaji Number:J876.616I
Wikidata:Q82294186
Mol file:193887-70-6.mol

Synonyms:4-AZIDO-3-CHLOROBENZYL BROMIDE;193887-70-6;1-azido-4-(bromomethyl)-2-chlorobenzene;p-azido-m-chlorobenzyl bromide;DTXSID50467306;KWLVILKXNKDWCB-UHFFFAOYSA-N

Suppliers and Price of 4-Azido-3-chlorobenzyl bromide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
1-AZIDO-4-(BROMOMETHYL)-2-CHLOROBENZENE 95.00%
5MG
$ 496.80

Total 4 raw suppliers

Chemical Property of 4-Azido-3-chlorobenzyl bromide

Chemical Property:

PSA：49.75000
LogP:3.62946
XLogP3:4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:244.93554
Heavy Atom Count:12
Complexity:193

Purity/Quality:

97% ^*data from raw suppliers

1-AZIDO-4-(BROMOMETHYL)-2-CHLOROBENZENE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=C(C=C1CBr)Cl)N=[N+]=[N-]

Technology Process of 4-Azido-3-chlorobenzyl bromide

There total 3 articles about 4-Azido-3-chlorobenzyl bromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 61.0%

: 136672-34-9
1-azido-2-chloro-4-methylbenzene

: C₇H₄Br₂ClN₃

: 193887-70-6
4-azido-3-chlorobenzyl bromide

Guidance literature:: With bromine; In tetrachloromethane; for 0.0236111h; Flow reactor; UV-irradiation;
DOI:10.1002/chem.201402303

Reference yield: 58.0%

: 136672-34-9
1-azido-2-chloro-4-methylbenzene

: 193887-70-6
4-azido-3-chlorobenzyl bromide

Guidance literature:: With N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile); In benzene; for 10h; Heating;
DOI:10.1055/s-1997-3258

Reference yield:

: 615-65-6
2-chloro-4-methyl-benzenamine

: 193887-70-6
4-azido-3-chlorobenzyl bromide

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) NaNO₂, conc. HCl; 2.) NaN₃ / 1.) DMF, water, 30 min; 2.) DMF, water, 1.5 h

2: 58 percent / NBS, 2,2'-azobisisobutironitrile / benzene / 10 h / Heating

With hydrogenchloride; N-Bromosuccinimide; sodium azide; 2,2'-azobis(isobutyronitrile); sodium nitrite; In benzene;
DOI:10.1055/s-1997-3258