(4-iso-butyl-benzyl)-[2-(4-chloro-3-ethyl-phenyl)-ethyl]-amine hydrochloride

Base Information

• Chemical Name: (4-iso-butyl-benzyl)-[2-(4-chloro-3-ethyl-phenyl)-ethyl]-amine hydrochloride
• CAS No.: 1352659-91-6
• Molecular Formula: C₂₁H₂₈ClN*ClH
• Molecular Weight: 366.374
• Mol file: 1352659-91-6.mol

Synonyms:(4-iso-butyl-benzyl)-[2-(4-chloro-3-ethyl-phenyl)-ethyl]-amine hydrochloride

Chemical Property of (4-iso-butyl-benzyl)-[2-(4-chloro-3-ethyl-phenyl)-ethyl]-amine hydrochloride

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of (4-iso-butyl-benzyl)-[2-(4-chloro-3-ethyl-phenyl)-ethyl]-amine hydrochloride

There total 1 articles about (4-iso-butyl-benzyl)-[2-(4-chloro-3-ethyl-phenyl)-ethyl]-amine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C21H26ClN → (4-iso-butyl-benzyl)-[2-(4-chloro-3-ethyl-phenyl)-ethyl]-amine hydrochloride (1352659-91-6)

Guidance literature:

C₂₁H₂₆ClN; With sodium tetrahydroborate; In methanol; at 20 ℃; for 17.5h; Cooling with ice;

With water; In methanol; at 20 ℃;

With hydrogenchloride; In water; ethyl acetate; at 20 ℃;

Reference yield: 98.9%

3-chloro-2-fluoro-5-(trifluoromethyl)benzoic acid (129931-45-9) + (4-iso-butyl-benzyl)-[2-(4-chloro-3-ethyl-phenyl)-ethyl]-amine hydrochloride (1352659-91-6) → N-(4-iso-butyl-benzyl)-3-chloro-N-[2-(4-chloro-3-ethyl-phenyl)-ethyl]-2-fluoro-5-trifluoromethyl-benzamide (1352659-76-7)

Guidance literature:

With O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; triethylamine; In tetrahydrofuran; at 20 ℃; for 18.5h; Inert atmosphere;

Downstream raw materials:

N-(4-iso-butyl-benzyl)-3-chloro-N-[2-(4-chloro-3-ethyl-phenyl)-ethyl]-2-fluoro-5-trifluoromethyl-benzamide