3,4-Pyridinediamine, N4,2,6-trimethyl-

Base Information

• Chemical Name: 3,4-Pyridinediamine, N4,2,6-trimethyl-
• CAS No.: 193690-78-7
• Molecular Formula: C8H13 N3
• Molecular Weight: 151.21
• Mol file: 193690-78-7.mol

Synonyms:3,4-Pyridinediamine, N4,2,6-trimethyl-

Chemical Property of 3,4-Pyridinediamine, N4,2,6-trimethyl-

Chemical Property:

• PSA: 50.94000
• LogP: 1.97650

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3,4-Pyridinediamine, N4,2,6-trimethyl-

There total 7 articles about 3,4-Pyridinediamine, N4,2,6-trimethyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

2,6-dimethyl-4-methylamino-3-nitropyridine (193690-77-6) → 3-amino-2,6-dimethyl-4-(methylamino)pyridine (193690-78-7)

Guidance literature:

With hydrogen; palladium on activated charcoal; In ethanol; for 18h; under 2585.7 Torr; Ambient temperature;

DOI:10.1002/jhet.5570340303

Reference yield:

2,6-dimethylpyridine (108-48-5) → 3-amino-2,6-dimethyl-4-(methylamino)pyridine (193690-78-7)

Guidance literature:

Multi-step reaction with 5 steps

1: 5 percent / sodium amide / 140 - 150 °C

2: 100 percent / K₂CO₃ / acetone / 5 h / Ambient temperature

3: 98 percent / lithium aluminum hydride / tetrahydrofuran / 0.5 h / Heating

4: 15 percent / H₂SO₄, HNO₃ / 0.08 h / Heating

5: 100 percent / H₂ / 10percent Pd/C / aq. ethanol / 18 h / 2585.7 Torr / Ambient temperature

With lithium aluminium tetrahydride; sulfuric acid; hydrogen; nitric acid; potassium carbonate; sodium amide; palladium on activated charcoal; In tetrahydrofuran; ethanol; acetone;

DOI:10.1002/jhet.5570340303

Reference yield:

4-amino-2,6-lutidine (3512-80-9) → 3-amino-2,6-dimethyl-4-(methylamino)pyridine (193690-78-7)

Guidance literature:

Multi-step reaction with 4 steps

1: 100 percent / K₂CO₃ / acetone / 5 h / Ambient temperature

2: 98 percent / lithium aluminum hydride / tetrahydrofuran / 0.5 h / Heating

3: 15 percent / H₂SO₄, HNO₃ / 0.08 h / Heating

4: 100 percent / H₂ / 10percent Pd/C / aq. ethanol / 18 h / 2585.7 Torr / Ambient temperature

With lithium aluminium tetrahydride; sulfuric acid; hydrogen; nitric acid; potassium carbonate; palladium on activated charcoal; In tetrahydrofuran; ethanol; acetone;

DOI:10.1002/jhet.5570340303

upstream raw materials:

2,6-dimethyl-4-methylamino-3-nitropyridine

2,6-dimethylpyridine

4-amino-2,6-lutidine

2,6-lutidine N-oxide

Downstream raw materials:

4-methyl-N-(1,4,6-trimethyl-1H-imidazo[4,5-c]pyridin-2-yl)-benzenesulfonamide