N-{2-[(S)-2-(tert-butyldimethylsilyl)-1,1-dioxo-1,2-thiazetidin-3-yl]acetyl}glycyl-L-nitroarginine benzyl ester

Base Information

Chemical Name:N-{2-[(S)-2-(tert-butyldimethylsilyl)-1,1-dioxo-1,2-thiazetidin-3-yl]acetyl}glycyl-L-nitroarginine benzyl ester
CAS No.:840525-45-3
Molecular Formula:C₂₅H₄₁N₇O₈SSi
Molecular Weight:627.794
Hs Code.:

Synonyms:N-{2-[(S)-2-(tert-butyldimethylsilyl)-1,1-dioxo-1,2-thiazetidin-3-yl]acetyl}glycyl-L-nitroarginine benzyl ester

Suppliers and Price of N-{2-[(S)-2-(tert-butyldimethylsilyl)-1,1-dioxo-1,2-thiazetidin-3-yl]acetyl}glycyl-L-nitroarginine benzyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-{2-[(S)-2-(tert-butyldimethylsilyl)-1,1-dioxo-1,2-thiazetidin-3-yl]acetyl}glycyl-L-nitroarginine benzyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N-{2-[(S)-2-(tert-butyldimethylsilyl)-1,1-dioxo-1,2-thiazetidin-3-yl]acetyl}glycyl-L-nitroarginine benzyl ester

There total 3 articles about N-{2-[(S)-2-(tert-butyldimethylsilyl)-1,1-dioxo-1,2-thiazetidin-3-yl]acetyl}glycyl-L-nitroarginine benzyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 28.0%

: 840525-46-4
2,5-dioxopyrolidin-1-yl (S)-2-(tert-butyldimethylsilyl)-1,1-dioxo-1,2-thiazetidin-3-acetate

: Boc-Gly-L-Arg(NO₂)-OBn hydrochloride

: 840525-45-3
N-{2-[(S)-2-(tert-butyldimethylsilyl)-1,1-dioxo-1,2-thiazetidin-3-yl]acetyl}glycyl-L-nitroarginine benzyl ester

Guidance literature:: With triethylamine; In tetrahydrofuran; acetonitrile; at 20 ℃; for 72h;

Reference yield:

: 840525-37-3
benzyl (S)-2-(tert-butyldimethylsilyl)-1,2-thiazetidin-3-acetate 1,1-dioxide

: 840525-45-3
N-{2-[(S)-2-(tert-butyldimethylsilyl)-1,1-dioxo-1,2-thiazetidin-3-yl]acetyl}glycyl-L-nitroarginine benzyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 70 percent / H₂ / 10 percent Pd/C / ethanol

2: 96 percent / dicyclohexyl carbodiimide / tetrahydrofuran / 1 h / -12 °C

3: 28 percent / Et₃N / tetrahydrofuran; acetonitrile / 72 h / 20 °C

With hydrogen; triethylamine; dicyclohexyl-carbodiimide; palladium on activated charcoal; In tetrahydrofuran; ethanol; acetonitrile;

Reference yield:

: 840525-38-4
(S)-2-(tert-butyldimethylsilyl)-1,2-thiazetidin-3-acetic acid 1,1-dioxide

: 840525-45-3
N-{2-[(S)-2-(tert-butyldimethylsilyl)-1,1-dioxo-1,2-thiazetidin-3-yl]acetyl}glycyl-L-nitroarginine benzyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 96 percent / dicyclohexyl carbodiimide / tetrahydrofuran / 1 h / -12 °C

2: 28 percent / Et₃N / tetrahydrofuran; acetonitrile / 72 h / 20 °C

With triethylamine; dicyclohexyl-carbodiimide; In tetrahydrofuran; acetonitrile;