1-Ethenylthieno[2,3-d]imidazole-5-carboxylic acid

Base Information

Chemical Name:1-Ethenylthieno[2,3-d]imidazole-5-carboxylic acid
CAS No.:193066-57-8
Molecular Formula:C₈H₆N₂O₂S
Molecular Weight:194.214
Hs Code.:
DSSTox Substance ID:DTXSID70571419
Wikidata:Q82459499
Mol file:193066-57-8.mol

Synonyms:193066-57-8;1-Ethenylthieno[2,3-d]imidazole-5-carboxylic acid;1H-Thieno[2,3-d]imidazole-5-carboxylic acid, 1-ethenyl-;DTXSID70571419;1-Ethenyl-1H-thieno[2,3-d]imidazole-5-carboxylic acid

Suppliers and Price of 1-Ethenylthieno[2,3-d]imidazole-5-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

AccelPharmtech
1-ethenyl-1H-Thieno[2,3-d]imidazole-5-carboxylicacid 97.00%
25G
$ 13300.00

Total 1 raw suppliers

Chemical Property of 1-Ethenylthieno[2,3-d]imidazole-5-carboxylic acid

Chemical Property:

PSA：83.36000
LogP:1.89650
XLogP3:1.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:194.01499861
Heavy Atom Count:13
Complexity:246

Purity/Quality:: 1-ethenyl-1H-Thieno[2,3-d]imidazole-5-carboxylicacid 97.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C=CN1C=NC2=C1C=C(S2)C(=O)O

Technology Process of 1-Ethenylthieno[2,3-d]imidazole-5-carboxylic acid

There total 6 articles about 1-Ethenylthieno[2,3-d]imidazole-5-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 193066-56-7
1-Vinyl-1H-thieno[2,3-d]imidazole-5-carboxylic acid ethyl ester

: 193066-57-8
1-Vinyl-1H-thieno[2,3-d]imidazole-5-carboxylic acid

Guidance literature:: With lithium hydroxide; In tetrahydrofuran; Heating;
DOI:10.1016/S0040-4039(97)00957-X

Reference yield:

: 41205-31-6
2,4,5-tribromo-1-vinylimidazole

: 193066-57-8
1-Vinyl-1H-thieno[2,3-d]imidazole-5-carboxylic acid

Guidance literature:: Multi-step reaction with 6 steps

1: EtMgBr / diethyl ether / 0 °C

2: 81 percent / H⁺

3: EtMgBr / diethyl ether / 0 °C

5: 61 percent / K₂CO₃ / dimethylformamide / Ambient temperature

6: 90 percent / LiOH / tetrahydrofuran / Heating

With lithium hydroxide; ethylmagnesium bromide; hydrogen cation; potassium carbonate; In tetrahydrofuran; diethyl ether; N,N-dimethyl-formamide;
DOI:10.1016/S0040-4039(97)00957-X

Reference yield:

: 193066-55-6
4-bromo-1-vinylimidazole-5-carbaldehyde

: 193066-57-8
1-Vinyl-1H-thieno[2,3-d]imidazole-5-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 61 percent / K₂CO₃ / dimethylformamide / Ambient temperature

2: 90 percent / LiOH / tetrahydrofuran / Heating

With lithium hydroxide; potassium carbonate; In tetrahydrofuran; N,N-dimethyl-formamide;
DOI:10.1016/S0040-4039(97)00957-X