N-cyano-N-(m-phenoxybenzyl)<(1R,3S)-2,2-dimethyl-3-(2-methyl-1-propenyl)cyclopropylmethyl>amine

Base Information

• Chemical Name: N-cyano-N-(m-phenoxybenzyl)<(1R,3S)-2,2-dimethyl-3-(2-methyl-1-propenyl)cyclopropylmethyl>amine
• CAS No.: 160193-56-6
• Molecular Formula: C₂₄H₂₈N₂O
• Molecular Weight: 360.499
• Mol file: 160193-56-6.mol

Synonyms:N-cyano-N-(m-phenoxybenzyl)<(1R,3S)-2,2-dimethyl-3-(2-methyl-1-propenyl)cyclopropylmethyl>amine

Chemical Property of N-cyano-N-(m-phenoxybenzyl)<(1R,3S)-2,2-dimethyl-3-(2-methyl-1-propenyl)cyclopropylmethyl>amine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-cyano-N-(m-phenoxybenzyl)<(1R,3S)-2,2-dimethyl-3-(2-methyl-1-propenyl)cyclopropylmethyl>amine

There total 10 articles about N-cyano-N-(m-phenoxybenzyl)<(1R,3S)-2,2-dimethyl-3-(2-methyl-1-propenyl)cyclopropylmethyl>amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

3-phenoxybenzyl chloride (53874-66-1) + N-cyano-<(1R,3S)-2,2-dimethyl-3-(2-methyl-1-propenyl)cyclopropylmethyl>amine (160193-55-5) → N-cyano-N-(m-phenoxybenzyl)<(1R,3S)-2,2-dimethyl-3-(2-methyl-1-propenyl)cyclopropylmethyl>amine (160193-56-6)

Guidance literature:

With N-benzyl-N,N,N-triethylammonium chloride; In potassium hydroxide; dichloromethane; for 2h; Heating;

DOI:10.1055/s-1994-25608

Reference yield: 78.0%

3-phenoxybenzyl chloride (53874-66-1) + (1R,3S)-2,2-dimethyl-3-(2-methyl-1-propenyl)cyclopropylacetamide O-tosyloxime (160193-57-7) → N-cyano-N-(m-phenoxybenzyl)<(1R,3S)-2,2-dimethyl-3-(2-methyl-1-propenyl)cyclopropylmethyl>amine (160193-56-6)

Guidance literature:

With N-benzyl-N,N,N-triethylammonium chloride; In potassium hydroxide; dichloromethane; for 2h; Heating;

DOI:10.1055/s-1994-25608

Reference yield:

3-phenoxybenzyl chloride (53874-66-1) → N-cyano-N-(m-phenoxybenzyl)<(1R,3S)-2,2-dimethyl-3-(2-methyl-1-propenyl)cyclopropylmethyl>amine (160193-56-6)

Guidance literature:

Multi-step reaction with 3 steps

1: 80 percent / benzyltriethylammonium chloride / CH₂Cl₂; aq. KOH / 2 h / Heating

2: 85 percent / diethyl ether / 2 h / Heating

3: POCl₃, pyridine / 0 °C

With pyridine; N-benzyl-N,N,N-triethylammonium chloride; trichlorophosphate; In potassium hydroxide; diethyl ether; dichloromethane;

DOI:10.1055/s-1994-25608

upstream raw materials:

3-phenoxybenzyl chloride

N-cyano-<(1R,3S)-2,2-dimethyl-3-(2-methyl-1-propenyl)cyclopropylmethyl>amine

(1R,3S)-2,2-dimethyl-3-(2-methyl-1-propenyl)cyclopropylacetamide O-tosyloxime

N-cyano-N-(m-phenoxybenzyl)<(1R,3S)-2,2-dimethyl-3-(2-hydroxy-2-methylpropyl)cyclopropylmethyl>amine