(R)-(+)-methyl 3-<4-<2-ethoxy>phenyl>-2-hydroxypropanoate

Base Information

Chemical Name:(R)-(+)-methyl 3-<4-<2-ethoxy>phenyl>-2-hydroxypropanoate
CAS No.:239478-56-9
Molecular Formula:C₂₀H₂₂N₂O₅
Molecular Weight:370.405
Hs Code.:

(R)-(+)-methyl 3-<4-<2-<N-(2-benzoxazolyl)-N-methylamino>ethoxy>phenyl>-2-hydroxypropanoate

Synonyms:(R)-(+)-methyl 3-<4-<2-ethoxy>phenyl>-2-hydroxypropanoate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (R)-(+)-methyl 3-<4-<2-ethoxy>phenyl>-2-hydroxypropanoate

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Technology Process of (R)-(+)-methyl 3-<4-<2-ethoxy>phenyl>-2-hydroxypropanoate

There total 4 articles about (R)-(+)-methyl 3-<4-<2-ethoxy>phenyl>-2-hydroxypropanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 43.0%

: 108-05-4,9003-20-7
vinyl acetate

: 158062-59-0
methyl 3-<4-<2-ethoxy>phenyl>-2-hydroxypropanoate

: 239478-56-9
(R)-(+)-methyl 3-<4-<2-ethoxy>phenyl>-2-hydroxypropanoate

: 239478-57-0
(S)-(+)-methyl 3-<4-<2-ethoxy>phenyl>-2-acetoxypropanoate

Guidance literature:: With pseudomonas fluorescens lipase; for 144h; Ambient temperature;
DOI:10.1016/S0968-0896(99)00034-6

Reference yield:

: 128316-64-3,481072-37-1
(+/-)-methyl 3-p-benzyloxyphenyl-2-hydroxypropionate

: 239478-56-9
(R)-(+)-methyl 3-<4-<2-ethoxy>phenyl>-2-hydroxypropanoate

Guidance literature:: Multi-step reaction with 3 steps

1: 97 percent / H₂ / Pd/C / methanol / Ambient temperature

2: 37 percent / NaH / dimethylformamide / 16 h / 80 °C

3: 39 percent / Pseudomonas Fluorescens lipase / 144 h / Ambient temperature

With pseudomonas fluorescens lipase; hydrogen; sodium hydride; palladium on activated charcoal; In methanol; N,N-dimethyl-formamide;
DOI:10.1016/S0968-0896(99)00034-6

Reference yield:

: 51095-47-7
methyl 3-(4-hydroxyphenyl)-2-hydroxypropionate

: 239478-56-9
(R)-(+)-methyl 3-<4-<2-ethoxy>phenyl>-2-hydroxypropanoate

Guidance literature:: Multi-step reaction with 2 steps

1: 37 percent / NaH / dimethylformamide / 16 h / 80 °C

2: 39 percent / Pseudomonas Fluorescens lipase / 144 h / Ambient temperature

With pseudomonas fluorescens lipase; sodium hydride; In N,N-dimethyl-formamide;
DOI:10.1016/S0968-0896(99)00034-6