2-[3'-cyano-4'-[4''-(methylthio)phenylethynyl]phenyl]-1,3-diethyl-1,3,2-benzodiazaborole

Base Information

Chemical Name:2-[3'-cyano-4'-[4''-(methylthio)phenylethynyl]phenyl]-1,3-diethyl-1,3,2-benzodiazaborole
CAS No.:1310330-64-3
Molecular Formula:C₂₆H₂₄BN₃S
Molecular Weight:421.374
Hs Code.:

Synonyms:2-[3'-cyano-4'-[4''-(methylthio)phenylethynyl]phenyl]-1,3-diethyl-1,3,2-benzodiazaborole

Suppliers and Price of 2-[3'-cyano-4'-[4''-(methylthio)phenylethynyl]phenyl]-1,3-diethyl-1,3,2-benzodiazaborole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2-[3'-cyano-4'-[4''-(methylthio)phenylethynyl]phenyl]-1,3-diethyl-1,3,2-benzodiazaborole

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-[3'-cyano-4'-[4''-(methylthio)phenylethynyl]phenyl]-1,3-diethyl-1,3,2-benzodiazaborole

There total 2 articles about 2-[3'-cyano-4'-[4''-(methylthio)phenylethynyl]phenyl]-1,3-diethyl-1,3,2-benzodiazaborole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

: 880499-54-7
5-bromo-2-([4-(methylthio)phenyl]ethynyl)benzonitrile

: 383913-07-3
2-bromo-1,3-diethyl-2,3-dihydro-1H-1,3,2-benzodiazoborole

: 1310330-64-3
2-[3'-cyano-4'-[4''-(methylthio)phenylethynyl]phenyl]-1,3-diethyl-1,3,2-benzodiazaborole

Guidance literature:: With n-butyllithium; In tetrahydrofuran; hexane; (Ar) to soln. arylbromide in THF at -110°C n-BuLi in hexane was added, stirred 20 min, soln. bromodiazaborole in THF was added, alowed to warm to r.t. and stirred for 16 h; soln. was evapd. to dryness, residue was extd. with n-hexane, ppt. was filtered, dried in vacuo and crystd. from CH2Cl2; elem. anal.;
DOI:10.1039/c0dt01410a

Reference yield:

: 56041-85-1
4-ethynylthioanisole

: 121554-10-7
5-bromo-2-iodobenzonitrile

: 1310330-64-3
2-[3'-cyano-4'-[4''-(methylthio)phenylethynyl]phenyl]-1,3-diethyl-1,3,2-benzodiazaborole

Guidance literature:: Multi-step reaction with 2 steps

1.1: copper(l) iodide; bis-triphenylphosphine-palladium(II) chloride; triethylamine / tetrahydrofuran / Inert atmosphere

2.1: n-butyllithium / tetrahydrofuran; hexane / -110 °C / Inert atmosphere

2.2: -110 - 20 °C / Inert atmosphere

With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; n-butyllithium; triethylamine; In tetrahydrofuran; hexane; 1.1: Sonogashira coupling;
DOI:10.1039/c0dt01410a