Cyclohexanecarboxylic acid, 1-methyl-3-oxo-, (R)-(9CI)

Base Information

Chemical Name:Cyclohexanecarboxylic acid, 1-methyl-3-oxo-, (R)-(9CI)
CAS No.:192433-20-8
Molecular Formula:C₈H₁₂O₃
Molecular Weight:156.181
Hs Code.:
DSSTox Substance ID:DTXSID00445290
Mol file:192433-20-8.mol

Synonyms:192433-20-8;Cyclohexanecarboxylic acid, 1-methyl-3-oxo-, (R)- (9CI);(1R)-1-METHYL-3-OXOCYCLOHEXANE-1-CARBOXYLIC ACID;CTK0H1464;Cyclohexanecarboxylic acid, 1-methyl-3-oxo-, (R)-(9CI);DTXSID00445290;(R)-1-Methyl-3-oxocyclohexanecarboxylic acid

Suppliers and Price of Cyclohexanecarboxylic acid, 1-methyl-3-oxo-, (R)-(9CI)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of Cyclohexanecarboxylic acid, 1-methyl-3-oxo-, (R)-(9CI)

Chemical Property:

PSA：54.37000
LogP:1.22040
XLogP3:0.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:156.078644241
Heavy Atom Count:11
Complexity:198

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1(CCCC(=O)C1)C(=O)O
Isomeric SMILES:C[C@]1(CCCC(=O)C1)C(=O)O

Technology Process of Cyclohexanecarboxylic acid, 1-methyl-3-oxo-, (R)-(9CI)

There total 5 articles about Cyclohexanecarboxylic acid, 1-methyl-3-oxo-, (R)-(9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1193-18-6
3-methylcyclohexen-2-one

: 192433-20-8
(R)-1-methyl-3-oxocyclohexane-1-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 1-((1R,2R)-2-aminocyclohexyl)-3-(3,5-bis(trifluoromethyl)phenyl)thiourea / 45 °C / Inert atmosphere

2: sodium nitrite; acetic acid / dimethyl sulfoxide / 6 h / 40 °C

With 1-((1R,2R)-2-aminocyclohexyl)-3-(3,5-bis(trifluoromethyl)phenyl)thiourea; acetic acid; sodium nitrite; In dimethyl sulfoxide;
DOI:10.1016/j.tet.2021.132005