methyl-[2-(1-oxo-4-phenyl-1H-phthalazin-2-yl)ethyl]carbamic acid tert-butyl ester

Base Information

• Chemical Name: methyl-[2-(1-oxo-4-phenyl-1H-phthalazin-2-yl)ethyl]carbamic acid tert-butyl ester
• CAS No.: 1146480-76-3
• Molecular Formula: C₂₂H₂₅N₃O₃
• Molecular Weight: 379.459
• Mol file: 1146480-76-3.mol

Synonyms:methyl-[2-(1-oxo-4-phenyl-1H-phthalazin-2-yl)ethyl]carbamic acid tert-butyl ester

Chemical Property of methyl-[2-(1-oxo-4-phenyl-1H-phthalazin-2-yl)ethyl]carbamic acid tert-butyl ester

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of methyl-[2-(1-oxo-4-phenyl-1H-phthalazin-2-yl)ethyl]carbamic acid tert-butyl ester

There total 1 articles about methyl-[2-(1-oxo-4-phenyl-1H-phthalazin-2-yl)ethyl]carbamic acid tert-butyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

4-phenyl-2H-phthalazin-1-one (5004-45-5) + methyl(2-hydroxyethyl)carbamic acid tert-butyl ester (57561-39-4) → methyl-[2-(1-oxo-4-phenyl-1H-phthalazin-2-yl)ethyl]carbamic acid tert-butyl ester (1146480-76-3)

Guidance literature:

4-phenyl-2H-phthalazin-1-one; With triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; toluene; at -10 ℃; for 0.25h; Inert atmosphere;

methyl(2-hydroxyethyl)carbamic acid tert-butyl ester; In tetrahydrofuran; toluene; at -10 - 20 ℃; for 22h; Inert atmosphere;

DOI:10.1080/00397911.2014.944269

Reference yield:

methyl-[2-(1-oxo-4-phenyl-1H-phthalazin-2-yl)ethyl]carbamic acid tert-butyl ester (1146480-76-3) → 2-[2-(methylamino)-ethyl]-4-phenyl-2H-phthalazin-1-one

Guidance literature:

With hydrogenchloride; In water; at 20 ℃; for 30h;

DOI:10.1080/00397911.2014.944269

upstream raw materials:

4-phenyl-2H-phthalazin-1-one

methyl(2-hydroxyethyl)carbamic acid tert-butyl ester