3-(1,3-dimethyl-1H-pyrazol-5-yl)-1-[3-(trifluoromethoxy)benzyl]-1,2,3,4-tetrahydroquinoxaline

Base Information

Chemical Name:3-(1,3-dimethyl-1H-pyrazol-5-yl)-1-[3-(trifluoromethoxy)benzyl]-1,2,3,4-tetrahydroquinoxaline
CAS No.:1425037-58-6
Molecular Formula:C₂₁H₂₁F₃N₄O
Molecular Weight:402.419
Hs Code.:

Synonyms:3-(1,3-dimethyl-1H-pyrazol-5-yl)-1-[3-(trifluoromethoxy)benzyl]-1,2,3,4-tetrahydroquinoxaline

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Chemical Property of 3-(1,3-dimethyl-1H-pyrazol-5-yl)-1-[3-(trifluoromethoxy)benzyl]-1,2,3,4-tetrahydroquinoxaline

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Technology Process of 3-(1,3-dimethyl-1H-pyrazol-5-yl)-1-[3-(trifluoromethoxy)benzyl]-1,2,3,4-tetrahydroquinoxaline

There total 3 articles about 3-(1,3-dimethyl-1H-pyrazol-5-yl)-1-[3-(trifluoromethoxy)benzyl]-1,2,3,4-tetrahydroquinoxaline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1425037-56-4
2-(1,3-dimethyl-1H-pyrazol-5-yl)quinoxaline

: 52771-21-8,50823-91-1
3-(trifluoromethoxy)benzaldehyde

: 1425037-58-6
3-(1,3-dimethyl-1H-pyrazol-5-yl)-1-[3-(trifluoromethoxy)benzyl]-1,2,3,4-tetrahydroquinoxaline

Guidance literature:: With sodium tris(acetoxy)borohydride; acetic acid;

Reference yield:

: 25594-62-1
2-acetylquinoxaline

: 1425037-58-6
3-(1,3-dimethyl-1H-pyrazol-5-yl)-1-[3-(trifluoromethoxy)benzyl]-1,2,3,4-tetrahydroquinoxaline

Guidance literature:: Multi-step reaction with 4 steps

1: 3 h / 100 °C

2: acetic acid / 55 °C

3: borane-THF / tetrahydrofuran / 1 h / 0 °C

4: acetic acid; sodium tris(acetoxy)borohydride

With borane-THF; sodium tris(acetoxy)borohydride; acetic acid; In tetrahydrofuran;

Reference yield:

: 1425037-54-2
3-(dimethylamino)-1-(quinoxalin-2-yl)but-2-en-1-one

: 1425037-58-6
3-(1,3-dimethyl-1H-pyrazol-5-yl)-1-[3-(trifluoromethoxy)benzyl]-1,2,3,4-tetrahydroquinoxaline

Guidance literature:: Multi-step reaction with 3 steps

1: acetic acid / 55 °C

2: borane-THF / tetrahydrofuran / 1 h / 0 °C

3: acetic acid; sodium tris(acetoxy)borohydride

With borane-THF; sodium tris(acetoxy)borohydride; acetic acid; In tetrahydrofuran;