((8R,9S,13S,14S)-2,3-Bis-benzyloxy-13-methyl-7,8,9,11,12,13,14,15-octahydro-6H-cyclopenta[a]phenanthren-17-yloxy)-triethyl-silane

Base Information

Chemical Name:((8R,9S,13S,14S)-2,3-Bis-benzyloxy-13-methyl-7,8,9,11,12,13,14,15-octahydro-6H-cyclopenta[a]phenanthren-17-yloxy)-triethyl-silane
CAS No.:176219-91-3
Molecular Formula:C₃₈H₄₈O₃Si
Molecular Weight:580.883
Hs Code.:

Synonyms:((8R,9S,13S,14S)-2,3-Bis-benzyloxy-13-methyl-7,8,9,11,12,13,14,15-octahydro-6H-cyclopenta[a]phenanthren-17-yloxy)-triethyl-silane

Suppliers and Price of ((8R,9S,13S,14S)-2,3-Bis-benzyloxy-13-methyl-7,8,9,11,12,13,14,15-octahydro-6H-cyclopenta[a]phenanthren-17-yloxy)-triethyl-silane

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of ((8R,9S,13S,14S)-2,3-Bis-benzyloxy-13-methyl-7,8,9,11,12,13,14,15-octahydro-6H-cyclopenta[a]phenanthren-17-yloxy)-triethyl-silane

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of ((8R,9S,13S,14S)-2,3-Bis-benzyloxy-13-methyl-7,8,9,11,12,13,14,15-octahydro-6H-cyclopenta[a]phenanthren-17-yloxy)-triethyl-silane

There total 6 articles about ((8R,9S,13S,14S)-2,3-Bis-benzyloxy-13-methyl-7,8,9,11,12,13,14,15-octahydro-6H-cyclopenta[a]phenanthren-17-yloxy)-triethyl-silane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 79271-56-0
triethylsilyl trifluoromethyl sulfonate

: 51478-04-7
2,3-dibenzyloxy-1,3,5⁽¹⁰⁾-estratriene-17-one

: 176219-91-3
((8R,9S,13S,14S)-2,3-Bis-benzyloxy-13-methyl-7,8,9,11,12,13,14,15-octahydro-6H-cyclopenta[a]phenanthren-17-yloxy)-triethyl-silane

Guidance literature:: With triethylamine; In dichloromethane; at -78 ℃; for 2h;
DOI:10.1271/bbb.60.405

Reference yield:

: 38781-50-9
2-(17β-acetoxy-2-hydroxy-estra-1,3,5(10)-trien-3-yloxy)-5-nitro-benzophenone

: 176219-91-3
((8R,9S,13S,14S)-2,3-Bis-benzyloxy-13-methyl-7,8,9,11,12,13,14,15-octahydro-6H-cyclopenta[a]phenanthren-17-yloxy)-triethyl-silane

Guidance literature:: Multi-step reaction with 5 steps

1: 99.6 percent / Na₂CO₃ / dimethylformamide / 5 h / 100 - 120 °C

2: KOH / ethanol / 2 h / Heating

3: 224 mg / Na₂CO₃ / 20 h / 100 - 120 °C

4: 56.5 percent / Jones reagent / acetone / 0.05 h

5: 93 percent / Et₃N / CH₂Cl₂ / 2 h / -78 °C

With potassium hydroxide; jones reagent; sodium carbonate; triethylamine; In ethanol; dichloromethane; N,N-dimethyl-formamide; acetone;
DOI:10.1271/bbb.60.405

Reference yield:

: 100-44-7
benzyl chloride

: 176219-91-3
((8R,9S,13S,14S)-2,3-Bis-benzyloxy-13-methyl-7,8,9,11,12,13,14,15-octahydro-6H-cyclopenta[a]phenanthren-17-yloxy)-triethyl-silane

Guidance literature:: Multi-step reaction with 5 steps

1: 99.6 percent / Na₂CO₃ / dimethylformamide / 5 h / 100 - 120 °C

2: KOH / ethanol / 2 h / Heating

3: 224 mg / Na₂CO₃ / 20 h / 100 - 120 °C

4: 56.5 percent / Jones reagent / acetone / 0.05 h

5: 93 percent / Et₃N / CH₂Cl₂ / 2 h / -78 °C

With potassium hydroxide; jones reagent; sodium carbonate; triethylamine; In ethanol; dichloromethane; N,N-dimethyl-formamide; acetone;
DOI:10.1271/bbb.60.405