(R)-CTH-JAFAPHOS

Base Information

• Chemical Name: (R)-CTH-JAFAPHOS
• CAS No.: 191803-52-8
• Molecular Formula: C₄₈H₅₄FeN₂O₂P₂
• Molecular Weight: 808.763
• Mol file: 191803-52-8.mol

Synonyms:Ferrocene,1,1'-bis[[bis(1-methylethyl)amino]carbonyl]-2,2'-bis(diphenylphosphino)-,[S-(R*,R*)]-

Chemical Property of (R)-CTH-JAFAPHOS

Chemical Property:

• Melting Point: 206℃
• PSA: 33.66000
• LogP: 8.70910

Purity/Quality:

99%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (R)-CTH-JAFAPHOS

There total 1 articles about (R)-CTH-JAFAPHOS which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 49.0%

1,1'-N,N,N',N'-tetraisopropylferrocenedicarboxamide (107139-36-6) + chloro-diphenylphosphine (1079-66-9,74391-44-9) → meso-2,2'-bis(diphenylphosphino)-1,1'-N,N,N',N'-tetraisopropylferrocenedicarboxamide (821793-29-7,191876-91-2,872554-39-7,191803-52-8)

Guidance literature:

With (-)-sparteine; In diethyl ether; cyclohexane; addn. of soln. of s-BuLi in cyclohexane to a soln. of (-)-sparteine in ether at -78 °C under Ar, stirring for 10 min at -78 °C, addn. of Fe(C5H4CON(i-Pr)2)2 in ether, stirring for 2 h at -78 °C, addn. of Ph2PCl; addn. of aq. NH4Cl, extracton with CH2Cl2, concn. under reduced pressure, chromatography on silica gel deactivated with Et3N (EtOAc-hexane 1:6);

DOI:10.1139/V06-008

upstream raw materials:

1,1'-N,N,N',N'-tetraisopropylferrocenedicarboxamide

chloro-diphenylphosphine

Refernces