Technology Process of C25H26N2O4
There total 5 articles about C25H26N2O4 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
C26H29N2O5(1-)*Na(1+);
With
potassium hexamethylsilazane;
In
toluene;
at -78 - -20 ℃;
for 7h;
Inert atmosphere;
With
ammonium chloride;
In
water; toluene;
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: sodium tetrahydroborate; cerium(III) chloride heptahydrate / methanol / 3 h / 5 - 23 °C / Inert atmosphere
2.1: triethylamine / Immobilised Lipase PS "Amino" / 22 h / 23 °C / Inert atmosphere
3.1: ammonium formate / bis-triphenylphosphine-palladium(II) chloride / acetonitrile / 0.33 h / 100 - 105 °C / Inert atmosphere
4.1: sodium hexamethyldisilazane / tetrahydrofuran / 0.62 h / -78 - 20 °C / Inert atmosphere
4.2: 0.73 h / -78 - -60 °C / Inert atmosphere
5.1: potassium hexamethylsilazane / toluene / 7 h / -78 - -20 °C / Inert atmosphere
With
sodium tetrahydroborate; cerium(III) chloride heptahydrate; ammonium formate; sodium hexamethyldisilazane; potassium hexamethylsilazane; triethylamine;
bis-triphenylphosphine-palladium(II) chloride;
In
tetrahydrofuran; methanol; toluene; acetonitrile;
4.1: Michael Reaction / 4.2: Michael Reaction / 5.1: Claisen Condensation / 5.2: Claisen Condensation;
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: triethylamine / Immobilised Lipase PS "Amino" / 22 h / 23 °C / Inert atmosphere
2.1: ammonium formate / bis-triphenylphosphine-palladium(II) chloride / acetonitrile / 0.33 h / 100 - 105 °C / Inert atmosphere
3.1: sodium hexamethyldisilazane / tetrahydrofuran / 0.62 h / -78 - 20 °C / Inert atmosphere
3.2: 0.73 h / -78 - -60 °C / Inert atmosphere
4.1: potassium hexamethylsilazane / toluene / 7 h / -78 - -20 °C / Inert atmosphere
With
ammonium formate; sodium hexamethyldisilazane; potassium hexamethylsilazane; triethylamine;
bis-triphenylphosphine-palladium(II) chloride;
In
tetrahydrofuran; toluene; acetonitrile;
3.1: Michael Reaction / 3.2: Michael Reaction / 4.1: Claisen Condensation / 4.2: Claisen Condensation;