Trifluoro-methanesulfonic acid (1R,3R,3aS,6S,6aR)-6-(tert-butyl-diphenyl-silanyloxymethyl)-3-isopropyl-3-methoxy-3a-methyl-4-oxo-tetrahydro-furo[3,4-c]furan-1-ylmethyl ester

Base Information

Chemical Name:Trifluoro-methanesulfonic acid (1R,3R,3aS,6S,6aR)-6-(tert-butyl-diphenyl-silanyloxymethyl)-3-isopropyl-3-methoxy-3a-methyl-4-oxo-tetrahydro-furo[3,4-c]furan-1-ylmethyl ester
CAS No.:171924-84-8
Molecular Formula:C₃₀H₃₉F₃O₈SSi
Molecular Weight:644.782
Hs Code.:

Trifluoro-methanesulfonic acid (1R,3R,3aS,6S,6aR)-6-(tert-butyl-diphenyl-silanyloxymethyl)-3-isopropyl-3-methoxy-3a-methyl-4-oxo-tetrahydro-furo[3,4-c]furan-1-ylmethyl ester

Synonyms:Trifluoro-methanesulfonic acid (1R,3R,3aS,6S,6aR)-6-(tert-butyl-diphenyl-silanyloxymethyl)-3-isopropyl-3-methoxy-3a-methyl-4-oxo-tetrahydro-furo[3,4-c]furan-1-ylmethyl ester

Suppliers and Price of Trifluoro-methanesulfonic acid (1R,3R,3aS,6S,6aR)-6-(tert-butyl-diphenyl-silanyloxymethyl)-3-isopropyl-3-methoxy-3a-methyl-4-oxo-tetrahydro-furo[3,4-c]furan-1-ylmethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Trifluoro-methanesulfonic acid (1R,3R,3aS,6S,6aR)-6-(tert-butyl-diphenyl-silanyloxymethyl)-3-isopropyl-3-methoxy-3a-methyl-4-oxo-tetrahydro-furo[3,4-c]furan-1-ylmethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Trifluoro-methanesulfonic acid (1R,3R,3aS,6S,6aR)-6-(tert-butyl-diphenyl-silanyloxymethyl)-3-isopropyl-3-methoxy-3a-methyl-4-oxo-tetrahydro-furo[3,4-c]furan-1-ylmethyl ester

There total 1 articles about Trifluoro-methanesulfonic acid (1R,3R,3aS,6S,6aR)-6-(tert-butyl-diphenyl-silanyloxymethyl)-3-isopropyl-3-methoxy-3a-methyl-4-oxo-tetrahydro-furo[3,4-c]furan-1-ylmethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 358-23-6
trifluoromethylsulfonic anhydride

: 171924-83-7
(1S,4S,5R,6R,8R)-4-<(tert-butyldiphenylsiloxy)methyl>-6-(hydroxymethyl)-8-isopropyl-8-methoxy-1-methyl-3,7-dioxabicyclo<3.3.0>octan-2-one

: 171924-84-8
Trifluoro-methanesulfonic acid (1R,3R,3aS,6S,6aR)-6-(tert-butyl-diphenyl-silanyloxymethyl)-3-isopropyl-3-methoxy-3a-methyl-4-oxo-tetrahydro-furo[3,4-c]furan-1-ylmethyl ester

Guidance literature:: With triethylamine; In dichloromethane; at -78 ℃; for 0.25h; Yield given;
DOI:10.1021/jo00130a017

Reference yield: 57.0%

: 82782-13-6
5-ethyl-2-methyl-3(2H)-furanone

: 171924-84-8
Trifluoro-methanesulfonic acid (1R,3R,3aS,6S,6aR)-6-(tert-butyl-diphenyl-silanyloxymethyl)-3-isopropyl-3-methoxy-3a-methyl-4-oxo-tetrahydro-furo[3,4-c]furan-1-ylmethyl ester

: 172018-00-7
(3S,3aR,4S,6R,6aS)-3-(tert-Butyl-diphenyl-silanyloxymethyl)-4-((S)-5-ethyl-2-methyl-3-oxo-2,3-dihydro-furan-2-ylmethyl)-6-isopropyl-6-methoxy-6a-methyl-tetrahydro-furo[3,4-c]furan-1-one

: 171924-85-9
(3S,3aR,4S,6R,6aS)-3-(tert-Butyl-diphenyl-silanyloxymethyl)-4-((R)-5-ethyl-2-methyl-3-oxo-2,3-dihydro-furan-2-ylmethyl)-6-isopropyl-6-methoxy-6a-methyl-tetrahydro-furo[3,4-c]furan-1-one

Guidance literature:: With potassium hexamethylsilazane; In toluene; 1.) -78 deg C, 10 min, 2.) -78 deg C to 0 deg C, 2 h;
DOI:10.1021/jo00130a017

Reference yield:

: 171924-84-8
Trifluoro-methanesulfonic acid (1R,3R,3aS,6S,6aR)-6-(tert-butyl-diphenyl-silanyloxymethyl)-3-isopropyl-3-methoxy-3a-methyl-4-oxo-tetrahydro-furo[3,4-c]furan-1-ylmethyl ester

: 58030-93-6
(+)-eremantholide A

Guidance literature:: Multi-step reaction with 7 steps

1: 57 percent / KHMDS / toluene / 1.) -78 deg C, 10 min, 2.) -78 deg C to 0 deg C, 2 h

2: n-Bu₄NF / tetrahydrofuran / 0.33 h / Ambient temperature

3: (COCl)2, DMSO, Et₃N / CH₂Cl₂ / 1.) -78 deg C, 1 h, 2.) 0 deg C, 30 min

4: KHMDS, 18-crown-6 / tetrahydrofuran; toluene / 0.17 h / -78 °C

5: 91 percent / DMAP / pyridine / 24 h / Ambient temperature

6: 76 percent / DBU / toluene / 2 h / Heating

7: 82 percent / 6 M aq. HCl / tetrahydrofuran / 6 h / Ambient temperature

With hydrogenchloride; dmap; oxalyl dichloride; 18-crown-6 ether; tetrabutyl ammonium fluoride; potassium hexamethylsilazane; dimethyl sulfoxide; 1,8-diazabicyclo[5.4.0]undec-7-ene; triethylamine; In tetrahydrofuran; pyridine; dichloromethane; toluene;
DOI:10.1021/jo00130a017