3-PYRIDINEACETIC ACID, 4-[[(1,1-DIMETHYLETHOXY)CARBONYL]AMINO]-A-OXO-, ETHYL ESTER

Base Information

Chemical Name:3-PYRIDINEACETIC ACID, 4-[[(1,1-DIMETHYLETHOXY)CARBONYL]AMINO]-A-OXO-, ETHYL ESTER
CAS No.:191338-96-2
Molecular Formula:C₁₄H₁₈N₂O₅
Molecular Weight:294.307
Hs Code.:
Mol file:191338-96-2.mol

Synonyms:[4-[(tert-Butoxycarbonyl)amino]pyridin-3-yl](oxo)aceticacid ethyl ester; [4-[(tert-Butoxycarbonyl)amino]pyridin-3-yl]glyoxylic acidethyl ester

Suppliers and Price of 3-PYRIDINEACETIC ACID, 4-[[(1,1-DIMETHYLETHOXY)CARBONYL]AMINO]-A-OXO-, ETHYL ESTER

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Labseeker
3-PYRIDINEACETICACID,4-[[(1,1-DIMETHYLETHOXY)CARBONYL]AMINO]-A-OXO-,ETHYLESTER 95
1g
$ 1283.00

American Custom Chemicals Corporation
3-PYRIDINEACETIC ACID, 4-[[(1,1-DIMETHYLETHOXY)CARBONYL]AMINO]-ALPHA-OXO-, ETHYL ESTER 95.00%
5MG
$ 501.37

Total 3 raw suppliers

Chemical Property of 3-PYRIDINEACETIC ACID, 4-[[(1,1-DIMETHYLETHOXY)CARBONYL]AMINO]-A-OXO-, ETHYL ESTER

Chemical Property:

PSA：94.59000
LogP:2.24740

Purity/Quality:

97% ^*data from raw suppliers

3-PYRIDINEACETICACID,4-[[(1,1-DIMETHYLETHOXY)CARBONYL]AMINO]-A-OXO-,ETHYLESTER 95 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 3-PYRIDINEACETIC ACID, 4-[[(1,1-DIMETHYLETHOXY)CARBONYL]AMINO]-A-OXO-, ETHYL ESTER

There total 2 articles about 3-PYRIDINEACETIC ACID, 4-[[(1,1-DIMETHYLETHOXY)CARBONYL]AMINO]-A-OXO-, ETHYL ESTER which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 20.0%

: 98400-69-2
N-(4-pyridyl) t-butyl carbamate

: 95-92-1
oxalic acid diethyl ester

: 191338-96-2
ethyl 2-(4-((tert-butoxycarbonyl)amino)pyridin-3-yl)-2-oxoacetate

Guidance literature:: N-(4-pyridyl) t-butyl carbamate; With n-butyllithium; In tetrahydrofuran; hexane; at -78 - -10 ℃; for 3h; Inert atmosphere;

oxalic acid diethyl ester; In tetrahydrofuran; hexane; at -78 - 20 ℃; for 0.5h; Inert atmosphere;
DOI:10.1021/acsmedchemlett.0c00422

Reference yield:

: 98400-69-2
N-(4-pyridyl) t-butyl carbamate

: 95-92-1
oxalic acid diethyl ester

: (4-N-tert-butoxycarbonylaminopyridin-3-yl)glyoxylic acid

: 191338-96-2
ethyl 2-(4-((tert-butoxycarbonyl)amino)pyridin-3-yl)-2-oxoacetate

Guidance literature:: With tert.-butyl lithium; Yield given. Multistep reaction. Yields of byproduct given; 1.) THF, hexane, -10 deg C, 3 h, 2.) THF, hexane, a) -78 deg C, 5 min, b) RT, 15 min;
DOI:10.1002/jhet.5570340213