4-(4-(3-oxa-8-azabicyclo[3.2.1]octan-8-yl)-6-thiomorpholino-1,3,5-triazin-2-yl)aniline

Base Information

Chemical Name:4-(4-(3-oxa-8-azabicyclo[3.2.1]octan-8-yl)-6-thiomorpholino-1,3,5-triazin-2-yl)aniline
CAS No.:1197164-43-4
Molecular Formula:C₁₉H₂₄N₆OS
Molecular Weight:384.505
Hs Code.:

Synonyms:4-(4-(3-oxa-8-azabicyclo[3.2.1]octan-8-yl)-6-thiomorpholino-1,3,5-triazin-2-yl)aniline

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Chemical Property of 4-(4-(3-oxa-8-azabicyclo[3.2.1]octan-8-yl)-6-thiomorpholino-1,3,5-triazin-2-yl)aniline

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Technology Process of 4-(4-(3-oxa-8-azabicyclo[3.2.1]octan-8-yl)-6-thiomorpholino-1,3,5-triazin-2-yl)aniline

There total 4 articles about 4-(4-(3-oxa-8-azabicyclo[3.2.1]octan-8-yl)-6-thiomorpholino-1,3,5-triazin-2-yl)aniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

: 1197164-42-3
8-(4-(4-nitrophenyl)-6-thiomorpholino-1,3,5-triazin-2-yl)-3-oxa-8-azabicyclo[3.2.1]octane

: 1197164-43-4
4-(4-(3-oxa-8-azabicyclo[3.2.1]octan-8-yl)-6-thiomorpholino-1,3,5-triazin-2-yl)aniline

Guidance literature:: With pyridine; tin(II) chloride dihdyrate; In N,N-dimethyl-formamide; at 20 ℃; for 16h;

Reference yield:

: 904316-92-3
3-oxa-8-azabicyclo[3.2.1]octane hydrochloride

: 1197164-43-4
4-(4-(3-oxa-8-azabicyclo[3.2.1]octan-8-yl)-6-thiomorpholino-1,3,5-triazin-2-yl)aniline

Guidance literature:: Multi-step reaction with 3 steps

1: sodium hydrogencarbonate / acetone; water / 20 h / 0 - 20 °C

2: sodium carbonate / acetone; water / 2.5 h / 60 °C

3: tin(II) chloride dihdyrate; pyridine / N,N-dimethyl-formamide / 16 h / 20 °C

With pyridine; tin(II) chloride dihdyrate; sodium hydrogencarbonate; sodium carbonate; In water; N,N-dimethyl-formamide; acetone;

Reference yield:

: 90415-38-6
2,4-dichloro-6-(4-nitrophenyl)-1,3,5-triazine

: 1197164-43-4
4-(4-(3-oxa-8-azabicyclo[3.2.1]octan-8-yl)-6-thiomorpholino-1,3,5-triazin-2-yl)aniline

Guidance literature:: Multi-step reaction with 3 steps

1: sodium hydrogencarbonate / acetone; water / 20 h / 0 - 20 °C

2: sodium carbonate / acetone; water / 2.5 h / 60 °C

3: tin(II) chloride dihdyrate; pyridine / N,N-dimethyl-formamide / 16 h / 20 °C

With pyridine; tin(II) chloride dihdyrate; sodium hydrogencarbonate; sodium carbonate; In water; N,N-dimethyl-formamide; acetone;