Technology Process of 4-<4-(1,1-dimethylheptyl)-2-hydroxyphenyl>-2-pentanol
There total 11 articles about 4-<4-(1,1-dimethylheptyl)-2-hydroxyphenyl>-2-pentanol which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
hydrogen; sodium hydrogencarbonate;
palladium on activated charcoal;
In
ethanol;
for 2h;
under 760 Torr;
Yield given;
DOI:10.1021/jm00367a013
- Guidance literature:
-
Multi-step reaction with 4 steps
1: Mg / tetrahydrofuran / 20 h / Heating
2: CuI / tetrahydrofuran / 0.5 h / -3 °C
3: NaBH4 / methanol; tetrahydrofuran / 1 h / -40 °C
4: H2, NaHCO3 / 10percent Pd/C / ethanol / 2 h / 760 Torr
With
sodium tetrahydroborate; copper(l) iodide; hydrogen; sodium hydrogencarbonate; magnesium;
palladium on activated charcoal;
In
tetrahydrofuran; methanol; ethanol;
DOI:10.1021/jm00367a013
- Guidance literature:
-
Multi-step reaction with 8 steps
1: 57 percent / DMSO, NaOH / 4 h / 15 °C
2: 78 percent / H2 / 10percent Pd/C / ethanol / 13 h / 2585.7 Torr
3: 100 percent / Br2 / CCl4 / 0.25 h / 30 °C
4: 1.) KH / 1.) DMF, -18 deg C, 15 min, 2.) 25 deg C, 30 min
5: Mg / tetrahydrofuran / 20 h / Heating
6: CuI / tetrahydrofuran / 0.5 h / -3 °C
7: NaBH4 / methanol; tetrahydrofuran / 1 h / -40 °C
8: H2, NaHCO3 / 10percent Pd/C / ethanol / 2 h / 760 Torr
With
sodium hydroxide; sodium tetrahydroborate; copper(l) iodide; hydrogen; bromine; potassium hydride; sodium hydrogencarbonate; magnesium; dimethyl sulfoxide;
palladium on activated charcoal;
In
tetrahydrofuran; methanol; tetrachloromethane; ethanol;
DOI:10.1021/jm00367a013
