(15S)-(E-but-2-enic acid morpholino amide)-3-estrone benzyl ether

Base Information

• Chemical Name: (15S)-(E-but-2-enic acid morpholino amide)-3-estrone benzyl ether
• CAS No.: 1030358-20-3
• Molecular Formula: C₃₃H₃₉NO₄
• Molecular Weight: 513.677
• Mol file: 1030358-20-3.mol

Synonyms:(15S)-(E-but-2-enic acid morpholino amide)-3-estrone benzyl ether

Chemical Property of (15S)-(E-but-2-enic acid morpholino amide)-3-estrone benzyl ether

Chemical Property:

Purity/Quality:

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Technology Process of (15S)-(E-but-2-enic acid morpholino amide)-3-estrone benzyl ether

There total 1 articles about (15S)-(E-but-2-enic acid morpholino amide)-3-estrone benzyl ether which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 51.0%

N-Acryloylmorpholine (5117-12-4,28902-82-1) + 15α-allyl-3-benzyloxyestra-1,3,5(10)-trien-17-one (534572-92-4) → (15S)-(E-but-2-enic acid morpholino amide)-3-estrone benzyl ether (1030358-20-3)

Guidance literature:

tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride; In dichloromethane; at 40 ℃; for 2.5h;

DOI:10.1016/j.tetlet.2008.02.134

upstream raw materials:

N-Acryloylmorpholine

15α-allyl-3-benzyloxyestra-1,3,5(10)-trien-17-one