Technology Process of C17H11BrFNO4
There total 5 articles about C17H11BrFNO4 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
C16H10Br2FNO3;
With
isopropylmagnesium chloride;
In
toluene;
at -78 - -20 ℃;
for 4h;
N,N-dimethyl-formamide;
In
ISOPROPYLAMIDE;
at -78 - 20 ℃;
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: isopropylmagnesium chloride / tetrahydrofuran; n-heptane; toluene / 1.83 h / -50 - 20 °C
1.2: -10 - 20 °C
2.1: toluene-4-sulfonic acid / n-heptane; toluene / 100 °C / Heating / reflux
3.1: sodium hydroxide; water / 1,2-dimethoxyethane; toluene / 0.5 h / -20 - 25 °C
3.2: 0 °C / pH 6 - 7
4.1: potassium carbonate / ISOPROPYLAMIDE / 0.08 h
4.2: 0.92 h / 125 °C
5.1: isopropylmagnesium chloride / toluene / 4 h / -78 - -20 °C
5.2: -78 - 20 °C
With
sodium hydroxide; water; isopropylmagnesium chloride; potassium carbonate;
toluene-4-sulfonic acid;
In
tetrahydrofuran; 1,2-dimethoxyethane; n-heptane; ISOPROPYLAMIDE; toluene;
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: toluene-4-sulfonic acid / n-heptane; toluene / 100 °C / Heating / reflux
2.1: sodium hydroxide; water / 1,2-dimethoxyethane; toluene / 0.5 h / -20 - 25 °C
2.2: 0 °C / pH 6 - 7
3.1: potassium carbonate / ISOPROPYLAMIDE / 0.08 h
3.2: 0.92 h / 125 °C
4.1: isopropylmagnesium chloride / toluene / 4 h / -78 - -20 °C
4.2: -78 - 20 °C
With
sodium hydroxide; water; isopropylmagnesium chloride; potassium carbonate;
toluene-4-sulfonic acid;
In
1,2-dimethoxyethane; n-heptane; ISOPROPYLAMIDE; toluene;
