(S)-5-[1-(2-methoxymethylpyrrolidinyl)sulfonyl]-1-[4-(oxiran-2-ylmethoxy)benzyl]isatin

Base Information

Chemical Name:(S)-5-[1-(2-methoxymethylpyrrolidinyl)sulfonyl]-1-[4-(oxiran-2-ylmethoxy)benzyl]isatin
CAS No.:1160524-51-5
Molecular Formula:C₂₄H₂₆N₂O₇S
Molecular Weight:486.546
Hs Code.:

Synonyms:(S)-5-[1-(2-methoxymethylpyrrolidinyl)sulfonyl]-1-[4-(oxiran-2-ylmethoxy)benzyl]isatin

Suppliers and Price of (S)-5-[1-(2-methoxymethylpyrrolidinyl)sulfonyl]-1-[4-(oxiran-2-ylmethoxy)benzyl]isatin

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (S)-5-[1-(2-methoxymethylpyrrolidinyl)sulfonyl]-1-[4-(oxiran-2-ylmethoxy)benzyl]isatin

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (S)-5-[1-(2-methoxymethylpyrrolidinyl)sulfonyl]-1-[4-(oxiran-2-ylmethoxy)benzyl]isatin

There total 1 articles about (S)-5-[1-(2-methoxymethylpyrrolidinyl)sulfonyl]-1-[4-(oxiran-2-ylmethoxy)benzyl]isatin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: 1160524-46-8
2-[(4-(chloromethyl)phenoxy)methyl]oxirane

: 220509-74-0,1110670-49-9
(S)-5-[1-(2-methoxymethylpyrrolidinyl)sulfonyl]isatin

: 1160524-51-5
(S)-5-[1-(2-methoxymethylpyrrolidinyl)sulfonyl]-1-[4-(oxiran-2-ylmethoxy)benzyl]isatin

Guidance literature:: (S)-5-[1-(2-methoxymethylpyrrolidinyl)sulfonyl]isatin; With potassium carbonate; In N,N-dimethyl-formamide; at 20 ℃; for 0.5h; Inert atmosphere;

2-[(4-(chloromethyl)phenoxy)methyl]oxirane; In N,N-dimethyl-formamide; at 0 - 20 ℃; for 8.5h; optical yield given as %de; Inert atmosphere;
DOI:10.1021/jm8015014

Reference yield: 45.0%

: 1160524-51-5
(S)-5-[1-(2-methoxymethylpyrrolidinyl)sulfonyl]-1-[4-(oxiran-2-ylmethoxy)benzyl]isatin

: 1160524-57-1
(S)-1-[4-(3-fluoro-2-hydroxypropoxy)benzyl]-5-[1-(2-methoxymethylpyrrolidinyl)sulfonyl]isatin

Guidance literature:: With triethylamine tris(hydrogen fluoride); In dichloromethane; for 16h; regioselective reaction; Inert atmosphere; Heating;
DOI:10.1021/jm8015014