2-(5-chloro-6-methyl-3-(2-morpholinoethylamino)-2-oxopyrazin-1(2H)-yl)-2-phenylacetic acid methyl ester

Base Information

Chemical Name:2-(5-chloro-6-methyl-3-(2-morpholinoethylamino)-2-oxopyrazin-1(2H)-yl)-2-phenylacetic acid methyl ester
CAS No.:1251933-05-7
Molecular Formula:C₂₀H₂₅ClN₄O₄
Molecular Weight:420.896
Hs Code.:

Synonyms:2-(5-chloro-6-methyl-3-(2-morpholinoethylamino)-2-oxopyrazin-1(2H)-yl)-2-phenylacetic acid methyl ester

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Chemical Property of 2-(5-chloro-6-methyl-3-(2-morpholinoethylamino)-2-oxopyrazin-1(2H)-yl)-2-phenylacetic acid methyl ester

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Technology Process of 2-(5-chloro-6-methyl-3-(2-morpholinoethylamino)-2-oxopyrazin-1(2H)-yl)-2-phenylacetic acid methyl ester

There total 1 articles about 2-(5-chloro-6-methyl-3-(2-morpholinoethylamino)-2-oxopyrazin-1(2H)-yl)-2-phenylacetic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 2038-03-1
4-(2-AMINOETHYL)MORPHOLINE

: 1178896-02-0,1251932-92-9
2-(3,5-dichloro-6-methyl-2-oxopyrazin-1(2H)-yl)-2-phenylacetic acid methyl ester

: 1251933-05-7
2-(5-chloro-6-methyl-3-(2-morpholinoethylamino)-2-oxopyrazin-1(2H)-yl)-2-phenylacetic acid methyl ester

Guidance literature:: With N-ethyl-N,N-diisopropylamine; In acetonitrile; at 100 ℃; for 1h; Microwave irradiation; Sealed vial;
DOI:10.1016/j.bmc.2010.06.101

Reference yield:

: 1251933-05-7
2-(5-chloro-6-methyl-3-(2-morpholinoethylamino)-2-oxopyrazin-1(2H)-yl)-2-phenylacetic acid methyl ester

: 1251933-83-1
C₁₉H₂₃ClN₄O₄

Guidance literature:: 2-(5-chloro-6-methyl-3-(2-morpholinoethylamino)-2-oxopyrazin-1(2H)-yl)-2-phenylacetic acid methyl ester; With water; potassium carbonate; In acetonitrile; at 120 ℃; for 0.75h; Microwave irradiation; Sealed vial;

With hydrogenchloride; In water; ethyl acetate; pH=2;
DOI:10.1016/j.bmc.2010.06.101