(E)-trimethyl(4-phenylbut phenylbut-1-en-1-yl)silane

Base Information

• Chemical Name: (E)-trimethyl(4-phenylbut phenylbut-1-en-1-yl)silane
• CAS No.: 101859-68-1
• Molecular Formula: C₁₄H₂₀
• Molecular Weight: 188.313
• Mol file: 101859-68-1.mol

Synonyms:(E)-trimethyl(4-phenylbut phenylbut-1-en-1-yl)silane

Chemical Property of (E)-trimethyl(4-phenylbut phenylbut-1-en-1-yl)silane

Chemical Property:

Purity/Quality:

Safty Information:

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• Hazard Codes: 

MSDS Files:

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Technology Process of (E)-trimethyl(4-phenylbut phenylbut-1-en-1-yl)silane

There total 10 articles about (E)-trimethyl(4-phenylbut phenylbut-1-en-1-yl)silane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

(2S,3S)-2-tert-Butyl-3-phenethyl-thiirane → (E)-trimethyl(4-phenylbut phenylbut-1-en-1-yl)silane (101859-68-1)

Guidance literature:

With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 1h;

DOI:10.1021/ja00271a030

Reference yield: 74.0%

3-phenyl-propionaldehyde (104-53-0) → (E)-trimethyl(4-phenylbut phenylbut-1-en-1-yl)silane (101859-68-1)

Guidance literature:

With C₁₆H₄₂Cl₄Cr₂N₄Si; zinc(II) chloride; In tetrahydrofuran; at 25 ℃; for 4h; Reagent/catalyst; Inert atmosphere;

DOI:10.1021/jacs.7b07487

Reference yield: 14.0%

3-phenyl-propionaldehyde (104-53-0) → 2-benzyl-5-phenyl-pent-2-enal (85908-07-2,70925-40-5) + (E)-trimethyl(4-phenylbut phenylbut-1-en-1-yl)silane (101859-68-1)

Guidance literature:

With C₁₆H₄₂Cl₄Cr₂N₄Si; cobalt(II) chloride; In tetrahydrofuran; at 25 ℃; for 4h; Inert atmosphere;

DOI:10.1021/jacs.7b07487

upstream raw materials:

C₄H₉Cl₂La

(Z)-4-phenyl-1-trimethylsilyl-1,2-epoxybutane

tert.-butyl lithium

4-Phenyl-1-butyne

Refernces

• 1、 Murai, Masahito,Taniguchi, Ryuji,Hosokawa, Naoki,Nishida, Yusuke,Mimachi, Hiroko,Oshiki, Toshiyuki,Takai, Kazuhiko. "Structural Characterization and Unique Catalytic Performance of Silyl-Group-Substituted Geminal Dichromiomethane Complexes Stabilized with a Diamine Ligand". supporting information. p. 13184 - 13192. Retrieved 2017/09/26.
• 2、 Ukaji, Yutaka,Yoshida, Akifumi,Fujisawa, Tamotsu. "Stereoselective Syntheses of Carbon Homologated Vinylsilanes and Desilylated Olefins from α,β-Epoxy Silanes Using Organolithium and Organolanthanoid Reagents". . p. 157 - 160. Retrieved 2007/10/02.