1-Brom-2-phenyl-<1-13C>ethan

Base Information

• Chemical Name: 1-Brom-2-phenyl-<1-13C>ethan
• CAS No.: 61415-35-8
• Molecular Formula: C₈H₉Br
• Molecular Weight: 186.052
• Mol file: 61415-35-8.mol

Synonyms:1-Brom-2-phenyl-<1-13C>ethan

Chemical Property of 1-Brom-2-phenyl-<1-13C>ethan

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-Brom-2-phenyl-<1-13C>ethan

There total 1 articles about 1-Brom-2-phenyl-<1-13C>ethan which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

<α-13C>phenethyl alcohol (35462-98-7) → 1-Brom-2-phenyl-<1-13C>ethan (61415-35-8)

Guidance literature:

With bromine; triphenylphosphine; In dichloromethane; at 20 ℃; for 1.5h;

DOI:10.1016/j.jorganchem.2007.11.009

Reference yield: 78.0%

1-Brom-2-phenyl-<1-13C>ethan (61415-35-8) → <1-13C>-2-Phenylaethen (61415-37-0)

Guidance literature:

With 1,8-diazabicyclo[5.4.0]undec-7-ene;

DOI:10.1021/ja00400a047

Reference yield: 64.0%

chloro[2,3,7,8,12,13,17,18-octachloro-5,10,15,20-tetrakis(p-tert-butylphenyl)porphyrinato](benzonitrile)rhodium(III) (213481-25-5) + 1-Brom-2-phenyl-<1-13C>ethan (61415-35-8) → [2,3,7,8,12,13,17,18-octachloro-5,10,15,20-tetrakis(p-tert-butylphenyl)porphyrinato]phenethyl-1-(13)C-rhodium(III) (213481-40-4)

Guidance literature:

With sodium hydroxide; sodium tetrahydroborate; In ethanol; water; under N2 atm. to suspn. Rh complex in EtOH soln. NaBH4 in aq. 0.1 M NaOHwas added and heated at 50°C for 1 h, soln. was cooled to 30.deg ree.C, EtBr was added and stirred at room temp. for 15 min; react. mixt. was worked up by extraction with CH2Cl2/H2O, org. phase wasdried over MgSO4, filtered and evapd., residue was purified by column c hromy. on silica;

DOI:10.1016/j.jorganchem.2007.11.009

upstream raw materials:

<α-13C>phenethyl alcohol

Downstream raw materials:

2-<1-(13C)-Phenethyl>-1.3-<13C>-malonsaeure-diethylester

<1-13C>-2-Phenylaethen

(E)-(β-13C)-β-bromostyrene

[2,3,7,8,12,13,17,18-octachloro-5,10,15,20-tetrakis(p-tert-butylphenyl)porphyrinato]phenethyl-1-⁽¹³⁾C-rhodium(III)