(4-Aminophenyl)(4-methylpyridin-2-yl)methanol

Base Information

Chemical Name:(4-Aminophenyl)(4-methylpyridin-2-yl)methanol
CAS No.:497854-56-5
Molecular Formula:C₁₃H₁₄N₂O
Molecular Weight:214.267
Hs Code.:
DSSTox Substance ID:DTXSID101250641

Synonyms:(4-aminophenyl)(4-methylpyridin-2-yl)methanol;497854-56-5;SCHEMBL5655486;WFCNUALLKPQXEV-UHFFFAOYSA-N;DTXSID101250641;(4-aminophenyl) (4-methylpyridin-2-yl)methanol;alpha-(4-Aminophenyl)-4-methyl-2-pyridinemethanol

Suppliers and Price of (4-Aminophenyl)(4-methylpyridin-2-yl)methanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (4-Aminophenyl)(4-methylpyridin-2-yl)methanol

Chemical Property:

XLogP3:1.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:214.110613074
Heavy Atom Count:16
Complexity:214

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=CC(=NC=C1)C(C2=CC=C(C=C2)N)O

Technology Process of (4-Aminophenyl)(4-methylpyridin-2-yl)methanol

There total 5 articles about (4-Aminophenyl)(4-methylpyridin-2-yl)methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: (4-azido-phenyl)-(4-methyl-pyridin-2-yl)-methanone

: 497854-56-5
(4-aminophenyl)(4-methylpyridin-2-yl)methanol

Guidance literature:: With lithium aluminium tetrahydride; In tetrahydrofuran; at 20 ℃;
DOI:10.1248/cpb.52.818

Reference yield:

: 497854-55-4
(4-fluorophenyl)(4-methylpyridin-2-yl)methanone

: 497854-56-5
(4-aminophenyl)(4-methylpyridin-2-yl)methanol

Guidance literature:: Multi-step reaction with 2 steps

1: 100 percent / NaN₃ / dimethylsulfoxide / 90 °C

2: 100 percent / LiAlH₄ / tetrahydrofuran / 20 °C

With lithium aluminium tetrahydride; sodium azide; In tetrahydrofuran; dimethyl sulfoxide;
DOI:10.1248/cpb.52.818

Reference yield:

: 4926-28-7
2-Bromo-4-picoline

: 497854-56-5
(4-aminophenyl)(4-methylpyridin-2-yl)methanol

Guidance literature:: Multi-step reaction with 4 steps

1: 46 percent / sodium 4-methylbenzenesulfinate; NaH / tetrahydrofuran / Heating

2: 55 percent / K₂CO₃; O₂ / dimethylsulfoxide; H₂O / 20 °C

3: 100 percent / NaN₃ / dimethylsulfoxide / 90 °C

4: 100 percent / LiAlH₄ / tetrahydrofuran / 20 °C

With lithium aluminium tetrahydride; sodium azide; oxygen; sodium hydride; potassium carbonate; sodium 4-methylbenzenesulfinate; In tetrahydrofuran; water; dimethyl sulfoxide;
DOI:10.1248/cpb.52.818