4-Chloro-5-fluoro-2-[[(1R)-1-phenyl-3-[(3 3.3-trifluoropropyl)amino]propyl]oxy]benzonitrile trifluoroacetate

Base Information

• Chemical Name: 4-Chloro-5-fluoro-2-[[(1R)-1-phenyl-3-[(3 3.3-trifluoropropyl)amino]propyl]oxy]benzonitrile trifluoroacetate
• CAS No.: 357402-81-4
• Molecular Formula: C₂HF₃O₂*C₁₉H₁₇ClF₄N₂O
• Molecular Weight: 514.827
• Mol file: 357402-81-4.mol

Synonyms:4-Chloro-5-fluoro-2-[[(1R)-1-phenyl-3-[(3 3.3-trifluoropropyl)amino]propyl]oxy]benzonitrile trifluoroacetate

Chemical Property of 4-Chloro-5-fluoro-2-[[(1R)-1-phenyl-3-[(3 3.3-trifluoropropyl)amino]propyl]oxy]benzonitrile trifluoroacetate

Chemical Property:

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Safty Information:

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MSDS Files:

Useful:

Technology Process of 4-Chloro-5-fluoro-2-[[(1R)-1-phenyl-3-[(3 3.3-trifluoropropyl)amino]propyl]oxy]benzonitrile trifluoroacetate

There total 1 articles about 4-Chloro-5-fluoro-2-[[(1R)-1-phenyl-3-[(3 3.3-trifluoropropyl)amino]propyl]oxy]benzonitrile trifluoroacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-[[(1R)-3-amino-1-phenylpropyl]oxy]-4-chloro-5-fluorobenzonitrile (357402-60-9) + 3,3,3-trifluoropropanal (460-40-2) → 4-Chloro-5-fluoro-2-[[(1R)-1-phenyl-3-[(3 3.3-trifluoropropyl)amino]propyl]oxy]benzonitrile trifluoroacetate (357402-81-4)

Guidance literature:

With sodium tris(acetoxy)borohydride; In dichloromethane;

upstream raw materials:

2-[[(1R)-3-amino-1-phenylpropyl]oxy]-4-chloro-5-fluorobenzonitrile

3,3,3-trifluoropropanal