C₂₆H₂₇NO₄

Base Information

• Chemical Name: C₂₆H₂₇NO₄
• CAS No.: 850748-19-5
• Molecular Formula: C₂₆H₂₇NO₄
• Molecular Weight: 417.505
• Mol file: 850748-19-5.mol

Synonyms:C₂₆H₂₇NO₄

Chemical Property of C₂₆H₂₇NO₄

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₆H₂₇NO₄

There total 9 articles about C₂₆H₂₇NO₄ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

C26H26BrNO4 (850748-18-4) → C26H27NO4 (850748-19-5)

Guidance literature:

With acetic acid; zinc; In methanol; for 4h; Heating;

DOI:10.1021/ol0473750

Reference yield:

(1R,4S,4aR,5R,8R,8aS)-1,4,4a,5,8,8a-Hexahydro-1,4-methano-naphthalene-5,8-diol → C26H27NO4 (850748-19-5)

Guidance literature:

Multi-step reaction with 5 steps

1.1: 93 percent / NBS / CH₂Cl₂ / 0.75 h / 0 °C

2.1: CH₂Cl₂ / 1.75 h / 0 °C

2.2: 91 percent / K₂CO₃ / methanol; H₂O / 18 h / 0 - 20 °C

3.1: 67 percent / NaOH; t-BuOCl; sodium citrate / K₂OsO₂(OH)4 / propan-1-ol; H₂O / 20 h / 20 °C

4.1: 92 percent / TBAI; NaH / dimethylformamide / 4.5 h / 0 - 20 °C

5.1: 86 percent / Zn; AcOH / methanol / 4 h / Heating

With sodium hydroxide; N-Bromosuccinimide; tert-butylhypochlorite; tetra-(n-butyl)ammonium iodide; sodium citrate; sodium hydride; acetic acid; zinc; potassium dioxotetrahydroxoosmate(VI); In methanol; propan-1-ol; dichloromethane; water; N,N-dimethyl-formamide;

DOI:10.1021/ol0473750

Reference yield:

C11H13BrO2 (850748-15-1) → C26H27NO4 (850748-19-5)

Guidance literature:

Multi-step reaction with 4 steps

1.1: CH₂Cl₂ / 1.75 h / 0 °C

1.2: 91 percent / K₂CO₃ / methanol; H₂O / 18 h / 0 - 20 °C

2.1: 67 percent / NaOH; t-BuOCl; sodium citrate / K₂OsO₂(OH)4 / propan-1-ol; H₂O / 20 h / 20 °C

3.1: 92 percent / TBAI; NaH / dimethylformamide / 4.5 h / 0 - 20 °C

4.1: 86 percent / Zn; AcOH / methanol / 4 h / Heating

With sodium hydroxide; tert-butylhypochlorite; tetra-(n-butyl)ammonium iodide; sodium citrate; sodium hydride; acetic acid; zinc; potassium dioxotetrahydroxoosmate(VI); In methanol; propan-1-ol; dichloromethane; water; N,N-dimethyl-formamide;

DOI:10.1021/ol0473750

upstream raw materials:

C₂₆H₂₆BrNO₄

C₁₁H₁₃BrO₂

C₁₂H₁₄BrNO₃

C₁₂H₁₄BrNO₄

Downstream raw materials:

(3aS,4S,5S,7aS)-3-Benzyl-4-benzyloxy-5-hydroxy-3a,4,5,7a-tetrahydro-3H-benzooxazol-2-one

(3aR,4S,5S,6S,7R,7aR)-3-Benzyl-4,5-bis-benzyloxy-6,7-dihydroxy-hexahydro-benzooxazol-2-one

(3aR,4R,5S,5aR,8aR,8bS)-6-Benzyl-4,5-bis-benzyloxy-hexahydro-[1,3]dioxolo[4',5':3,4]benzo[1,2-d]oxazol-7-one