(+/-)-6,6-diethyl-7-<formamidyl>oxy-2-phenyl-6,7-dihydro-5H-<1>pyridine

Base Information

Chemical Name:(+/-)-6,6-diethyl-7-<formamidyl>oxy-2-phenyl-6,7-dihydro-5H-<1>pyridine
CAS No.:247185-57-5
Molecular Formula:C₂₇H₃₀N₂O₂
Molecular Weight:414.547
Hs Code.:

(+/-)-6,6-diethyl-7-<<N-(R)-methylbenzyl>formamidyl>oxy-2-phenyl-6,7-dihydro-5H-<1>pyridine

Synonyms:(+/-)-6,6-diethyl-7-<formamidyl>oxy-2-phenyl-6,7-dihydro-5H-<1>pyridine

Suppliers and Price of (+/-)-6,6-diethyl-7-<formamidyl>oxy-2-phenyl-6,7-dihydro-5H-<1>pyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of (+/-)-6,6-diethyl-7-<formamidyl>oxy-2-phenyl-6,7-dihydro-5H-<1>pyridine

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Technology Process of (+/-)-6,6-diethyl-7-<formamidyl>oxy-2-phenyl-6,7-dihydro-5H-<1>pyridine

There total 4 articles about (+/-)-6,6-diethyl-7-<formamidyl>oxy-2-phenyl-6,7-dihydro-5H-<1>pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.7%

: 33375-06-3
(1R)-1-phenylethyl isocyanate

: 247185-56-4
(+/-)-6,6-diethyl-7-hydroxy-2-phenyl-6,7-dihydro-5H-<1>pyridine

: 247185-57-5
(+/-)-6,6-diethyl-7-<formamidyl>oxy-2-phenyl-6,7-dihydro-5H-<1>pyridine

Guidance literature:: In toluene; at 100 ℃; for 8h;
DOI:10.1016/S0957-4166(99)00247-5

Reference yield:

: 97360-42-4
7-hydroxy-2-phenyl-6,7-dihydro-5H-<1>pyridine

: 247185-57-5
(+/-)-6,6-diethyl-7-<formamidyl>oxy-2-phenyl-6,7-dihydro-5H-<1>pyridine

Guidance literature:: Multi-step reaction with 4 steps

1: 72.1 percent / pyridinium chlorochromate / CH₂Cl₂ / 10 h / 45 °C

2: 1.) KOt-Bu / 1.) CH₂Cl₂, RT, 30 min, 2.) CH₂Cl₂, RT, 13 h

3: 44.7 percent / LAH / tetrahydrofuran / 6 h / Ambient temperature

4: 99.7 percent / toluene / 8 h / 100 °C

With lithium aluminium tetrahydride; potassium tert-butylate; pyridinium chlorochromate; In tetrahydrofuran; dichloromethane; toluene;
DOI:10.1016/S0957-4166(99)00247-5

Reference yield:

: 247185-54-2
7-oxo-2-phenyl-6,7-dihydro-5H-<1>pyridine

: 247185-57-5
(+/-)-6,6-diethyl-7-<formamidyl>oxy-2-phenyl-6,7-dihydro-5H-<1>pyridine

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) KOt-Bu / 1.) CH₂Cl₂, RT, 30 min, 2.) CH₂Cl₂, RT, 13 h

2: 44.7 percent / LAH / tetrahydrofuran / 6 h / Ambient temperature

3: 99.7 percent / toluene / 8 h / 100 °C

With lithium aluminium tetrahydride; potassium tert-butylate; In tetrahydrofuran; toluene;
DOI:10.1016/S0957-4166(99)00247-5