2-butyl-2-(4-((6-(4-(trifluoromethyl)phenyl)hex-5-yn-1-yl)oxy)phenyl)hexanal

Base Information

Chemical Name:2-butyl-2-(4-((6-(4-(trifluoromethyl)phenyl)hex-5-yn-1-yl)oxy)phenyl)hexanal
CAS No.:1449744-29-9
Molecular Formula:C₂₉H₃₅F₃O₂
Molecular Weight:472.591
Hs Code.:

Synonyms:2-butyl-2-(4-((6-(4-(trifluoromethyl)phenyl)hex-5-yn-1-yl)oxy)phenyl)hexanal

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Chemical Property of 2-butyl-2-(4-((6-(4-(trifluoromethyl)phenyl)hex-5-yn-1-yl)oxy)phenyl)hexanal

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Technology Process of 2-butyl-2-(4-((6-(4-(trifluoromethyl)phenyl)hex-5-yn-1-yl)oxy)phenyl)hexanal

There total 5 articles about 2-butyl-2-(4-((6-(4-(trifluoromethyl)phenyl)hex-5-yn-1-yl)oxy)phenyl)hexanal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 104-47-2
p-methoxybenzylnitrile

: 1449744-29-9
2-butyl-2-(4-((6-(4-(trifluoromethyl)phenyl)hex-5-yn-1-yl)oxy)phenyl)hexanal

Guidance literature:: Multi-step reaction with 4 steps

1: sodium hexamethyldisilazane / Inert atmosphere; Schlenk technique

2: boron tribromide / dichloromethane / 0 °C / Inert atmosphere; Schlenk technique

3: diisobutylaluminium hydride / Inert atmosphere; Schlenk technique

4: potassium carbonate / N,N-dimethyl-formamide / Inert atmosphere; Schlenk technique

With sodium hexamethyldisilazane; boron tribromide; diisobutylaluminium hydride; potassium carbonate; In dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/ja4068707

Reference yield:

: 16254-47-0
α,α-Di-(n-butyl)-4-hydroxyphenylacetonitril

: 1449744-29-9
2-butyl-2-(4-((6-(4-(trifluoromethyl)phenyl)hex-5-yn-1-yl)oxy)phenyl)hexanal

Guidance literature:: Multi-step reaction with 2 steps

1: diisobutylaluminium hydride / Inert atmosphere; Schlenk technique

2: potassium carbonate / N,N-dimethyl-formamide / Inert atmosphere; Schlenk technique

With diisobutylaluminium hydride; potassium carbonate; In N,N-dimethyl-formamide;
DOI:10.1021/ja4068707

Reference yield:

: 14191-95-8
4-cyanomethylphenol

: 1449744-29-9
2-butyl-2-(4-((6-(4-(trifluoromethyl)phenyl)hex-5-yn-1-yl)oxy)phenyl)hexanal

Guidance literature:: Multi-step reaction with 3 steps

1: sodium hexamethyldisilazane / Inert atmosphere; Schlenk technique

2: diisobutylaluminium hydride / Inert atmosphere; Schlenk technique

3: potassium carbonate / N,N-dimethyl-formamide / Inert atmosphere; Schlenk technique

With sodium hexamethyldisilazane; diisobutylaluminium hydride; potassium carbonate; In N,N-dimethyl-formamide;
DOI:10.1021/ja4068707