1-benzyl-2--4-hydroxymethylimidazole

Base Information

Chemical Name:1-benzyl-2--4-hydroxymethylimidazole
CAS No.:102151-55-3
Molecular Formula:C₂₄H₂₂N₂O₂
Molecular Weight:370.451
Hs Code.:

1-benzyl-2-<p-(benzyloxy)-phenyl>-4-hydroxymethylimidazole

Synonyms:1-benzyl-2--4-hydroxymethylimidazole

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1-benzyl-2--4-hydroxymethylimidazole

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Technology Process of 1-benzyl-2--4-hydroxymethylimidazole

There total 2 articles about 1-benzyl-2--4-hydroxymethylimidazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 51.0%

: 102151-54-2
1-benzyl-2--4-carbobenzoxyimidazole

: 102151-55-3
1-benzyl-2--4-hydroxymethylimidazole

Guidance literature:: With lithium aluminium tetrahydride; sodium sulfate; In tetrahydrofuran;
DOI:10.1021/jm00156a028

Reference yield:

: 102151-53-1
2-imidazole-4-carboxylic acid

: 102151-55-3
1-benzyl-2--4-hydroxymethylimidazole

Guidance literature:: Multi-step reaction with 2 steps

1: 87 percent / NaH / dimethylformamide / 18 h

2: 51 percent / LAH, Na₂SO₄ / tetrahydrofuran

With lithium aluminium tetrahydride; sodium hydride; sodium sulfate; In tetrahydrofuran; N,N-dimethyl-formamide;
DOI:10.1021/jm00156a028