4-(2-Chloro-phenyl)-2-methyl-6-(2-piperazin-1-yl-ethoxymethyl)-1,4-dihydro-pyridine-3,5-dicarboxylic acid 5-ethyl ester 3-methyl ester

Base Information

• Chemical Name: 4-(2-Chloro-phenyl)-2-methyl-6-(2-piperazin-1-yl-ethoxymethyl)-1,4-dihydro-pyridine-3,5-dicarboxylic acid 5-ethyl ester 3-methyl ester
• CAS No.: 91748-27-5
• Molecular Formula: C₂₄H₃₂ClN₃O₅
• Molecular Weight: 477.988
• Mol file: 91748-27-5.mol

Synonyms:4-(2-Chloro-phenyl)-2-methyl-6-(2-piperazin-1-yl-ethoxymethyl)-1,4-dihydro-pyridine-3,5-dicarboxylic acid 5-ethyl ester 3-methyl ester

Chemical Property of 4-(2-Chloro-phenyl)-2-methyl-6-(2-piperazin-1-yl-ethoxymethyl)-1,4-dihydro-pyridine-3,5-dicarboxylic acid 5-ethyl ester 3-methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of 4-(2-Chloro-phenyl)-2-methyl-6-(2-piperazin-1-yl-ethoxymethyl)-1,4-dihydro-pyridine-3,5-dicarboxylic acid 5-ethyl ester 3-methyl ester

There total 1 articles about 4-(2-Chloro-phenyl)-2-methyl-6-(2-piperazin-1-yl-ethoxymethyl)-1,4-dihydro-pyridine-3,5-dicarboxylic acid 5-ethyl ester 3-methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-{2-[4-(4-Chloro-benzyl)-piperazin-1-yl]-ethoxymethyl}-4-(2-chloro-phenyl)-6-methyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid 3-ethyl ester 5-methyl ester; compound with oxalic acid (103069-07-4) → 4-(2-Chloro-phenyl)-2-methyl-6-(2-piperazin-1-yl-ethoxymethyl)-1,4-dihydro-pyridine-3,5-dicarboxylic acid 5-ethyl ester 3-methyl ester (91748-27-5)

Guidance literature:

With hydrogen; palladium on activated charcoal; In methanol; for 18h; under 2585.7 Torr; Ambient temperature;

DOI:10.1021/jm00159a022

upstream raw materials:

2-{2-[4-(4-Chloro-benzyl)-piperazin-1-yl]-ethoxymethyl}-4-(2-chloro-phenyl)-6-methyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid 3-ethyl ester 5-methyl ester; compound with oxalic acid