6-benzenesulfinyl-3,4-bis-(tert-butyl-dimethyl-silanyloxy)-3,4-dihydro-2H-pyran

Base Information

Chemical Name:6-benzenesulfinyl-3,4-bis-(tert-butyl-dimethyl-silanyloxy)-3,4-dihydro-2H-pyran
CAS No.:432038-16-9
Molecular Formula:C₂₃H₄₀O₄SSi₂
Molecular Weight:468.805
Hs Code.:

6-benzenesulfinyl-3,4-bis-(<i>tert</i>-butyl-dimethyl-silanyloxy)-3,4-dihydro-2<i>H</i>-pyran

Synonyms:6-benzenesulfinyl-3,4-bis-(tert-butyl-dimethyl-silanyloxy)-3,4-dihydro-2H-pyran

Suppliers and Price of 6-benzenesulfinyl-3,4-bis-(tert-butyl-dimethyl-silanyloxy)-3,4-dihydro-2H-pyran

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 6-benzenesulfinyl-3,4-bis-(tert-butyl-dimethyl-silanyloxy)-3,4-dihydro-2H-pyran

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Technology Process of 6-benzenesulfinyl-3,4-bis-(tert-butyl-dimethyl-silanyloxy)-3,4-dihydro-2H-pyran

There total 1 articles about 6-benzenesulfinyl-3,4-bis-(tert-butyl-dimethyl-silanyloxy)-3,4-dihydro-2H-pyran which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: (2S,3R,4S,5R)-2-Benzenesulfinyl-3,4,5-tris-(tert-butyl-dimethyl-silanyloxy)-tetrahydro-pyran

: 432038-16-9
6-benzenesulfinyl-3,4-bis-(tert-butyl-dimethyl-silanyloxy)-3,4-dihydro-2H-pyran

Guidance literature:: With lithium diisopropyl amide; In tetrahydrofuran; at -78 ℃; for 2h;
DOI:10.1039/b111071n

Reference yield:

: 432038-16-9
6-benzenesulfinyl-3,4-bis-(tert-butyl-dimethyl-silanyloxy)-3,4-dihydro-2H-pyran

: 54336-64-0,95037-06-2,104826-38-2,123482-90-6,134731-78-5,136846-30-5,2304-81-6,252039-52-4
(2S,3R,4E)-2-(N-stearoylamino)-4-octadecene-1,3-diol

Guidance literature:: Multi-step reaction with 8 steps

1.1: t-BuLi / tetrahydrofuran; diethyl ether / 0.08 h / -78 °C

1.2: CuBr*SMe₂ / diethyl ether; various solvent(s) / 12 h / -40 - 20 °C

1.3: H₂O

2.1: 82 percent / p-TsOH / CH₂Cl₂ / 2 h / 20 °C

3.1: 90 percent / Bu₄NF / tetrahydrofuran / 12 h / 20 °C

4.1: NaH; 15-crown-5 / tetrahydrofuran / 14 h / Heating

4.2: 93 percent / Bu₄NF / tetrahydrofuran

5.1: 59 percent / (PhO)2P(O)N₃; DIAD; PPh₃ / toluene / 12 h / 20 °C

6.1: 82 percent / p-TsOH / methanol / 12 h / 20 °C

7.1: Zn; NH₄Cl / methanol / 12 h / 20 °C

With 15-crown-5; di-isopropyl azodicarboxylate; diphenyl phosphoryl azide; tetrabutyl ammonium fluoride; tert.-butyl lithium; sodium hydride; ammonium chloride; toluene-4-sulfonic acid; triphenylphosphine; zinc; In tetrahydrofuran; methanol; diethyl ether; dichloromethane; toluene; 5.1: Mitsunobu reaction;
DOI:10.1039/b111071n

Reference yield:

: 432038-16-9
6-benzenesulfinyl-3,4-bis-(tert-butyl-dimethyl-silanyloxy)-3,4-dihydro-2H-pyran

: 123-78-4
(2S,3R,4E)-2-amino-4-octadecene-1,3-diol

Guidance literature:: Multi-step reaction with 7 steps

1.1: t-BuLi / tetrahydrofuran; diethyl ether / 0.08 h / -78 °C

1.2: CuBr*SMe₂ / diethyl ether; various solvent(s) / 12 h / -40 - 20 °C

1.3: H₂O

2.1: 82 percent / p-TsOH / CH₂Cl₂ / 2 h / 20 °C

3.1: 90 percent / Bu₄NF / tetrahydrofuran / 12 h / 20 °C

4.1: NaH; 15-crown-5 / tetrahydrofuran / 14 h / Heating

4.2: 93 percent / Bu₄NF / tetrahydrofuran

5.1: 59 percent / (PhO)2P(O)N₃; DIAD; PPh₃ / toluene / 12 h / 20 °C

6.1: 82 percent / p-TsOH / methanol / 12 h / 20 °C

7.1: Zn; NH₄Cl / methanol / 12 h / 20 °C

With 15-crown-5; di-isopropyl azodicarboxylate; diphenyl phosphoryl azide; tetrabutyl ammonium fluoride; tert.-butyl lithium; sodium hydride; ammonium chloride; toluene-4-sulfonic acid; triphenylphosphine; zinc; In tetrahydrofuran; methanol; diethyl ether; dichloromethane; toluene; 5.1: Mitsunobu reaction;
DOI:10.1039/b111071n