O-(benzyl 2-acetamido-4,6-O-isopropylidene-2-deoxy-α-D-glucopyranosid-3-yl)-D-lactoyl-L-alanyl-D-isoglutamine

Base Information

• Chemical Name: O-(benzyl 2-acetamido-4,6-O-isopropylidene-2-deoxy-α-D-glucopyranosid-3-yl)-D-lactoyl-L-alanyl-D-isoglutamine
• CAS No.: 122768-09-6
• Molecular Formula: C₂₉H₄₂N₄O₁₁
• Molecular Weight: 622.673
• Mol file: 122768-09-6.mol

Synonyms:O-(benzyl 2-acetamido-4,6-O-isopropylidene-2-deoxy-α-D-glucopyranosid-3-yl)-D-lactoyl-L-alanyl-D-isoglutamine

Chemical Property of O-(benzyl 2-acetamido-4,6-O-isopropylidene-2-deoxy-α-D-glucopyranosid-3-yl)-D-lactoyl-L-alanyl-D-isoglutamine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of O-(benzyl 2-acetamido-4,6-O-isopropylidene-2-deoxy-α-D-glucopyranosid-3-yl)-D-lactoyl-L-alanyl-D-isoglutamine

There total 1 articles about O-(benzyl 2-acetamido-4,6-O-isopropylidene-2-deoxy-α-D-glucopyranosid-3-yl)-D-lactoyl-L-alanyl-D-isoglutamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

benzyl (R)-4-((S)-2-((R)-2-(((4aR,6S,7R,8R,8aS)-7-acetamido-6-(benzyloxy)-2,2-dimethylhexahydropyrano[3,2-d][1,3]dioxin-8-yl)oxy)propanamido)propanamido)-5-amino-5-oxopentanoate (69323-69-9,75263-32-0,75283-18-0,77843-23-3,128779-65-7) → O-(benzyl 2-acetamido-4,6-O-isopropylidene-2-deoxy-α-D-glucopyranosid-3-yl)-D-lactoyl-L-alanyl-D-isoglutamine (122768-09-6)

Guidance literature:

With hydrogen; palladium on activated charcoal; for 1h;

DOI:10.1007/BF00598215

Reference yield:

(9-(2′-hydroxyethylamino)-1-nitroacridine) (81483-73-0) + 1-O-benzyl-2-acetamido-4,6-O-isopropylidene-2-deoxy-α-D-glucopyranosyl-(3->O)-D-lactoyl-L-alanyl-D-isoglutamine (122768-09-6) → (R)-4-{(S)-2-[2-((4aR,6S,7R,8R,8aS)-7-Acetylamino-6-benzyloxy-2,2-dimethyl-hexahydro-pyrano[3,2-d][1,3]dioxin-8-yloxy)-propionylamino]-propionylamino}-4-carbamoyl-butyric acid 2-(1-nitro-acridin-9-ylamino)-ethyl ester

Guidance literature:

With N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline; In pyridine; N,N-dimethyl-formamide; at 4 ℃; for 72h;

Reference yield:

3-(1-Nitro-acridin-9-ylamino)-propan-1-ol (125685-75-8) + 1-O-benzyl-2-acetamido-4,6-O-isopropylidene-2-deoxy-α-D-glucopyranosyl-(3->O)-D-lactoyl-L-alanyl-D-isoglutamine (122768-09-6) → (R)-4-{(S)-2-[2-((4aR,6S,7R,8R,8aS)-7-Acetylamino-6-benzyloxy-2,2-dimethyl-hexahydro-pyrano[3,2-d][1,3]dioxin-8-yloxy)-propionylamino]-propionylamino}-4-carbamoyl-butyric acid 3-(1-nitro-acridin-9-ylamino)-propyl ester

Guidance literature:

With N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline; In pyridine; N,N-dimethyl-formamide; at 4 ℃; for 72h;

upstream raw materials:

benzyl (R)-4-((S)-2-((R)-2-(((4aR,6S,7R,8R,8aS)-7-acetamido-6-(benzyloxy)-2,2-dimethylhexahydropyrano[3,2-d][1,3]dioxin-8-yl)oxy)propanamido)propanamido)-5-amino-5-oxopentanoate

Downstream raw materials:

2-acetamido-1-O-benzyl-2-deoxy-α-D-glucopyranosyl-(3->O)-D-lactoyl-L-alanyl-D-isoglutamylglycine methyl ester

O-(benzyl 2-acetamido-2-deoxy-α-D-glucopyranosid-3-yl)-D-lactoyl-L-alanyl-D-isoglutamine γ-octadecylamide

O-(benzyl 2-acetamido-4,6-O-isopropylidene-2-deoxy-α-D-glucopyranosid-3-yl)-D-lactoyl-L-alanyl-D-isoglutamine γ-octadecylamide