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Technology Process of N2-[2-[1-[(4-fluorophenyl)methyl]-1H-imidazol-5-yl]ethyl]-N1-cyclohexyl-1,2(R)-piperazinecarboxamide

N2-[2-[1-[(4-fluorophenyl)methyl]-1H-imidazol-5-yl]ethyl]-N1-cyclohexyl-1,2(R)-piperazinecarboxamide

Base Information
  • Chemical Name:N2-[2-[1-[(4-fluorophenyl)methyl]-1H-imidazol-5-yl]ethyl]-N1-cyclohexyl-1,2(R)-piperazinecarboxamide
  • CAS No.:281195-41-3
  • Molecular Formula:C24H33FN6O2
  • Molecular Weight:456.563
  • Hs Code.:
N<sub>2</sub>-[2-[1-[(4-fluorophenyl)methyl]-1H-imidazol-5-yl]ethyl]-N<sub>1</sub>-cyclohexyl-1,2(R)-piperazinecarboxamide

Synonyms:N2-[2-[1-[(4-fluorophenyl)methyl]-1H-imidazol-5-yl]ethyl]-N1-cyclohexyl-1,2(R)-piperazinecarboxamide

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Chemical Property of N2-[2-[1-[(4-fluorophenyl)methyl]-1H-imidazol-5-yl]ethyl]-N1-cyclohexyl-1,2(R)-piperazinecarboxamide
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Technology Process of N2-[2-[1-[(4-fluorophenyl)methyl]-1H-imidazol-5-yl]ethyl]-N1-cyclohexyl-1,2(R)-piperazinecarboxamide

There total 2 articles about N2-[2-[1-[(4-fluorophenyl)methyl]-1H-imidazol-5-yl]ethyl]-N1-cyclohexyl-1,2(R)-piperazinecarboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

1,1-dimethylethyl-1-[(cyclohexylamino)carbonyl]-2(R)-[[[[2-[1-(4-fluorophenyl)methyl]-1H-imidazol-5-yl]ethyl]amino]carbonyl]-4-piperazinecarboxylate
281195-40-2

1,1-dimethylethyl-1-[(cyclohexylamino)carbonyl]-2(R)-[[[[2-[1-(4-fluorophenyl)methyl]-1H-imidazol-5-yl]ethyl]amino]carbonyl]-4-piperazinecarboxylate

N<sub>2</sub>-[2-[1-[(4-fluorophenyl)methyl]-1H-imidazol-5-yl]ethyl]-N<sub>1</sub>-cyclohexyl-1,2(R)-piperazinecarboxamide
281195-41-3

N2-[2-[1-[(4-fluorophenyl)methyl]-1H-imidazol-5-yl]ethyl]-N1-cyclohexyl-1,2(R)-piperazinecarboxamide

Guidance literature:
With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 1h;

Reference yield:

N<sub>2</sub>-[2-[1-[(4-fluorophenyl)methyl]-1H-imidazol-5-yl]ethyl]-N<sub>1</sub>-cyclohexyl-1,2(R)-piperazinecarboxamide
281195-41-3

N2-[2-[1-[(4-fluorophenyl)methyl]-1H-imidazol-5-yl]ethyl]-N1-cyclohexyl-1,2(R)-piperazinecarboxamide

Guidance literature:
upstream raw materials:

1,1-dimethylethyl-1-[(cyclohexylamino)carbonyl]-2(R)-[[[[2-[1-(4-fluorophenyl)methyl]-1H-imidazol-5-yl]ethyl]amino]carbonyl]-4-piperazinecarboxylate

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