Methyl-3-O-acetyl-2-O-benzyl-6-desoxy-4-O-mesyl-α-D-glucopyranosid

Base Information

• Chemical Name: Methyl-3-O-acetyl-2-O-benzyl-6-desoxy-4-O-mesyl-α-D-glucopyranosid
• CAS No.: 99152-64-4
• Molecular Formula: C₁₇H₂₄O₈S
• Molecular Weight: 388.439
• Mol file: 99152-64-4.mol

Synonyms:Methyl-3-O-acetyl-2-O-benzyl-6-desoxy-4-O-mesyl-α-D-glucopyranosid

Chemical Property of Methyl-3-O-acetyl-2-O-benzyl-6-desoxy-4-O-mesyl-α-D-glucopyranosid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Methyl-3-O-acetyl-2-O-benzyl-6-desoxy-4-O-mesyl-α-D-glucopyranosid

There total 6 articles about Methyl-3-O-acetyl-2-O-benzyl-6-desoxy-4-O-mesyl-α-D-glucopyranosid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

Methyl-3-O-acetyl-2-O-benzyl-6-desoxy-6-iodo-4-O-mesyl-α-D-glucopyranosid (99152-63-3) → Methyl-3-O-acetyl-2-O-benzyl-6-desoxy-4-O-mesyl-α-D-glucopyranosid (99152-64-4)

Guidance literature:

With zinc; In diethyl ether; acetic acid; for 1h;

DOI:10.1016/0008-6215(85)85061-8

Reference yield:

methyl 2-O-benzyl-4,6-O-benzylidene-α-D-glucopyranoside (76375-66-1) → Methyl-3-O-acetyl-2-O-benzyl-6-desoxy-4-O-mesyl-α-D-glucopyranosid (99152-64-4)

Guidance literature:

Multi-step reaction with 5 steps

1: 94 percent / pyridine / 5 h / Ambient temperature

2: 89 percent / trifluoroacetic acid / methanol; H₂O / 3 h / 70 °C

3: 84 percent / pyridine / 6 h / Ambient temperature

4: 91 percent / NaI / butan-2-one / 6 h / 90 °C

5: 98 percent / Zn / diethyl ether; acetic acid / 1 h

With trifluoroacetic acid; sodium iodide; zinc; In pyridine; methanol; diethyl ether; water; acetic acid; butanone;

DOI:10.1016/0008-6215(85)85061-8

Reference yield:

methyl 3-O-acetyl-2-O-benzyl-α-D-glucopyranoside (99152-61-1) → Methyl-3-O-acetyl-2-O-benzyl-6-desoxy-4-O-mesyl-α-D-glucopyranosid (99152-64-4)

Guidance literature:

Multi-step reaction with 3 steps

1: 84 percent / pyridine / 6 h / Ambient temperature

2: 91 percent / NaI / butan-2-one / 6 h / 90 °C

3: 98 percent / Zn / diethyl ether; acetic acid / 1 h

With sodium iodide; zinc; In pyridine; diethyl ether; acetic acid; butanone;

DOI:10.1016/0008-6215(85)85061-8

upstream raw materials:

Methyl-3-O-acetyl-2-O-benzyl-6-desoxy-6-iodo-4-O-mesyl-α-D-glucopyranosid

methyl 2-O-benzyl-4,6-O-benzylidene-α-D-glucopyranoside

methyl 3-O-acetyl-2-O-benzyl-α-D-glucopyranoside

Methyl-3-O-acetyl-2-O-benzyl-4,6-di-O-mesyl-α-D-glucopyranosid

Downstream raw materials:

Methyl-4-azido-2-O-benzyl-3-O-chloracetyl-4,6-didesoxy-α-D-galactopyranosid

Methyl-4-azido-2-O-benzyl-4,6-didesoxy-α-D-galactopyranosid

Methyl-3-O-acetyl-4-azido-2-O-benzyl-4,6-didesoxy-α-D-galactopyranosid