Hexadecanoic acid (2R,3S,4R,5R,6R)-2-((2R,3R,4R,5S,6R)-4-benzyloxy-3-hexadecanoylamino-6-hexadecanoyloxymethyl-5-hydroxy-tetrahydro-pyran-2-yloxymethyl)-5-hexadecanoylamino-3-octanoyloxy-6-[((E)-propenyl)oxy]-tetrahydro-pyran-4-yl ester

Base Information

• Chemical Name: Hexadecanoic acid (2R,3S,4R,5R,6R)-2-((2R,3R,4R,5S,6R)-4-benzyloxy-3-hexadecanoylamino-6-hexadecanoyloxymethyl-5-hydroxy-tetrahydro-pyran-2-yloxymethyl)-5-hexadecanoylamino-3-octanoyloxy-6-[((E)-propenyl)oxy]-tetrahydro-pyran-4-yl ester
• CAS No.: 82755-07-5
• Molecular Formula: C₉₄H₁₆₈N₂O₁₄
• Molecular Weight: 1550.37
• Mol file: 82755-07-5.mol

Synonyms:Hexadecanoic acid (2R,3S,4R,5R,6R)-2-((2R,3R,4R,5S,6R)-4-benzyloxy-3-hexadecanoylamino-6-hexadecanoyloxymethyl-5-hydroxy-tetrahydro-pyran-2-yloxymethyl)-5-hexadecanoylamino-3-octanoyloxy-6-[((E)-propenyl)oxy]-tetrahydro-pyran-4-yl ester

Chemical Property of Hexadecanoic acid (2R,3S,4R,5R,6R)-2-((2R,3R,4R,5S,6R)-4-benzyloxy-3-hexadecanoylamino-6-hexadecanoyloxymethyl-5-hydroxy-tetrahydro-pyran-2-yloxymethyl)-5-hexadecanoylamino-3-octanoyloxy-6-[((E)-propenyl)oxy]-tetrahydro-pyran-4-yl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Hexadecanoic acid (2R,3S,4R,5R,6R)-2-((2R,3R,4R,5S,6R)-4-benzyloxy-3-hexadecanoylamino-6-hexadecanoyloxymethyl-5-hydroxy-tetrahydro-pyran-2-yloxymethyl)-5-hexadecanoylamino-3-octanoyloxy-6-[((E)-propenyl)oxy]-tetrahydro-pyran-4-yl ester

There total 1 articles about Hexadecanoic acid (2R,3S,4R,5R,6R)-2-((2R,3R,4R,5S,6R)-4-benzyloxy-3-hexadecanoylamino-6-hexadecanoyloxymethyl-5-hydroxy-tetrahydro-pyran-2-yloxymethyl)-5-hexadecanoylamino-3-octanoyloxy-6-[((E)-propenyl)oxy]-tetrahydro-pyran-4-yl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

Hexadecanoic acid (2R,3S,4R,5R,6R)-4-benzyloxy-5-hexadecanoylamino-6-{(2R,3S,4R,5R,6R)-5-hexadecanoylamino-4-hexadecanoyloxy-3-octanoyloxy-6-[((E)-propenyl)oxy]-tetrahydro-pyran-2-ylmethoxy}-3-(4-oxo-pentanoyloxy)-tetrahydro-pyran-2-ylmethyl ester (82771-23-1) → Hexadecanoic acid (2R,3S,4R,5R,6R)-2-((2R,3R,4R,5S,6R)-4-benzyloxy-3-hexadecanoylamino-6-hexadecanoyloxymethyl-5-hydroxy-tetrahydro-pyran-2-yloxymethyl)-5-hexadecanoylamino-3-octanoyloxy-6-[((E)-propenyl)oxy]-tetrahydro-pyran-4-yl ester (82755-07-5)

Guidance literature:

With hydrazine hydrate; In pyridine; chloroform; acetic acid; at 35 ℃; for 0.116667h;

Reference yield:

Hexadecanoic acid (2R,3S,4R,5R,6R)-2-((2R,3R,4R,5S,6R)-4-benzyloxy-3-hexadecanoylamino-6-hexadecanoyloxymethyl-5-hydroxy-tetrahydro-pyran-2-yloxymethyl)-5-hexadecanoylamino-3-octanoyloxy-6-[((E)-propenyl)oxy]-tetrahydro-pyran-4-yl ester (82755-07-5) + 2,2,2-trichloroethyl bis(1-hydroxybenzotriazolyl)phosphate → C102H173Cl3N5O17P

Guidance literature:

In pyridine; at 35 ℃; for 0.75h; Yield given;

Reference yield:

Hexadecanoic acid (2R,3S,4R,5R,6R)-2-((2R,3R,4R,5S,6R)-4-benzyloxy-3-hexadecanoylamino-6-hexadecanoyloxymethyl-5-hydroxy-tetrahydro-pyran-2-yloxymethyl)-5-hexadecanoylamino-3-octanoyloxy-6-[((E)-propenyl)oxy]-tetrahydro-pyran-4-yl ester (82755-07-5) → C97H168Br3Cl6N2O20P2(1-) + C97H168Br3Cl6N2O20P2(1-)

Guidance literature:

Multistep reaction;

DOI:10.1016/S0040-4039(00)87231-7

upstream raw materials:

Hexadecanoic acid (2R,3S,4R,5R,6R)-4-benzyloxy-5-hexadecanoylamino-6-{(2R,3S,4R,5R,6R)-5-hexadecanoylamino-4-hexadecanoyloxy-3-octanoyloxy-6-[((E)-propenyl)oxy]-tetrahydro-pyran-2-ylmethoxy}-3-(4-oxo-pentanoyloxy)-tetrahydro-pyran-2-ylmethyl ester